This research aims to determine the Next Generation Science Standards (NGSS) that must be present in the content of the activities of the chemistry curriculum for the tenth grade in Palestine and to identify the availability of the scientific and practice dimensions of these standards in activities, including in chemistry for the tenth grade in Palestine. The descriptive approach and a tool were used. Analysis of the content of the chemistry curriculum in light of the standards (NGSS). The ADDIE model was relied upon in its stages in educational design, through the analysis stage, design stage, development, and production stage, and the most important results are: achieving a deep understanding of scientific concepts, developing advanced scientific skills, improving the quality of education, meeting international educational standards, continuous evaluation, and sustainable development.