Postoperative Cognitive Dysfunction (POCD) refers to the condition of neurocognitive decline following surgery in a cognitive and sensory manner. There are several risk factors, which may be life-threatening for this condition. Neuropsychological assessment of this condition is very im-portant. In the present review, we discuss the association of apolipoprotein epsilon 4 (APOE ?4) and few miRNAs with POCD, and highlight the clinical importance for prognosis, diagnosis and treatment of POCD. Microarray is a genome analysis that can be used to determine DNA abnormalities. This current technique is rapid, efficient and high-throughout. Microarray techniques are widely used to di-agnose diseases, particularly in genetic disorder, chromosomal abnormalities, mutations, infectious diseases and disease-relevant biomarkers. MicroRNAs (miRNAs) are a class of non-coding RNAs that are widely found distributed in eukaryotes. Few miRNAs influence the nervous system development, and nerve damage repair. Microarray approach can be utilized to understand the miRNAs involved and their pathways in POCD development, unleashing their potential to be considered as a diagnostic marker for POCD. This paper summarizes and identifies the studies that use microarray based approaches for POCD analysis. Since the application of microarray in POCD is expanding, there is a need to review the current knowledge of this approach. 2020 Bentham Science Publishers.

The workers and employees in various institutions are subjected to different shifts and work schedules. The employees work not only at daytime but also during odd hours at night. The biological clock of an individual is often altered during night shifts. This affects the psychosocial well-being and circadian nutritional intake of the worker. Disturbance in circadian rhythm results in the development of metabolic disorders such as hypertension, dyslipidemia, dysglycemia, and abdominal obesity. In the present review, we discuss the nature of shift work, sleep/wake cycle of an individual, chrononutrition, dietary habits, and meal changes with regard to timing and frequency, related to shift work. We also discuss the relationship between nutritional intake and psychosocial well-being among shift workers. The review may be beneficial for prevention of metabolic disorders and maintaining sound psychological condition in shift workers. � 2020 by the authors. Licensee MDPI, Basel, Switzerland.

Archery involves repetitive isometric contraction of muscles, however, there is a paucity in scientific evidence that describes the muscle strength in those receiving archery training. This study aimed to determine the differences in maximum force in selected groups of muscles between healthy youth with regular archery training and those without any background of resistance training. A case-control study design was adopted to compare between youth with archery training as subjects (n = 40) and youth without any background of resistance training as control (n = 78). Both groups were matched based on age, race, education level, income, time spent for weekly physical activities, and body composition. Muscle strength was assessed via JTech Commander PowerTrack MMT and the forces were recorded in Pound-force (lbf). Subjects with archery training showed significantly (p < 0.05) higher mean of muscle strength’s maximal force as compared to the control group in shoulder motions such as higher abduction strength (11%), adduction strength (15%), flexion and extension strength (19%). Elbow motion showed significantly higher extension strength by 17%. Similarly, higher lower body muscle strength was also found in subjects with archery training as compared to subjects in the control group in their hip motions for abduction (16%) and adduction (21%) and knee motion for extension (25%). Training in archery has a significant impact on muscle strength of both upper and lower body as shown in these youths. Therefore, serious attention should be given archery and be further promoted as a physical activity in the enhancement of health. © 2020, Springer Nature Singapore Pte Ltd.

At high altitude, low oxygen partial pressure predisposes human body to hypobaric hypoxia that may lead to high-altitude illness. Currently, singing had been used for rehabilitation of patients with lung diseases but its role in high-altitude low oxygen environment is still scarce. This study aims to examine the effect of singing in improving oxygen saturation at different levels of high altitudes in a hypobaric chamber. Eight healthy volunteers were assigned to three interventions at three simulated altitudes (sea level, 3000 m and 5000 m). The oxygen saturation (SpO2) was measured via pulse oximetry under three conditions: no singing (NS), singing aloud (SA), and singing silently (SS). The “birthday song” was used as the standard song for 4 minutes. At sea level, mean NS SpO2 was 97.75% ± 1.04%. With SS, the level increased to 98.25% ± 1.04%. Mean SA SpO2 increased to 98.38% ± 0.92% (P < 0.05). At 3000 m, mean NS SpO2 was 92.75% ± 3.73% and rose to 94.50% ± 2.51% and 94.63% ± 2.00% respectively with SA and SS (P < 0.05). At 5000 m, NS level of 79.88P ± 3.60% increased to 82.13 ± 5.87 and 82.88% ± 7.12% with SA and SS respectively (P < 0.05). The repeated measure ANOVA showed significant difference for altitude (P < 0.001) and intervention (P = 0.05). In conclusion, singing both either “aloud” or “silently” significantly increased the level of SpO2 in simulated high altitude at 3000 m and above. The study suggests that singing as a potential intervention to improve oxygen saturation at high altitudes. Study with larger sample in hypobaric chamber as well as in real environment is recommended. © 2020 The Voice Foundation

At present, there is a paucity of Malaysian policy on paediatric first aid training for childcare providers. Thus, this study has developed a first aid module called FAT4CP© for childcare providers and aim to determine the acceptance level of the module and validate an instrument that evaluates the competency of their knowledge, attitude and confidence (KAC) in conducting first aid. Focusing on the content, graphics and design, evaluation of acceptance for the module involved 15 childcare providers with at least one year of experience in handling children at childcare centres and 15 healthcare professionals. Together with the module, an assessment tool was developed, with content and face validity assessed by content experts. A self-administrated questionnaire was distributed to 70 childcare providers to measure their first aid KAC. Construct validity of the questionnaire was examined using Exploratory Factor Analysis (EFA) with principal component methods and varimax rotation. Cronbach's α values were used to estimate the reliability of the questionnaire. This study revealed that the module was well accepted with a majority of the childcare providers (93.3%, n=14) indicated that they understood the information contained in the module. The first aid assessment tool was also found to be reliable in measuring knowledge, attitude and confidence among childcare providers with Cronbach's alpha of 0.56, 0.95 and 0.92, respectively. For content validity, the questionnaires were critically reviewed in terms of relevance, clarity, simplicity, and ambiguity. In conclusion, the findings of this study demonstrated that the module was well received, and the assessment tool is valid and reliable in measuring first aid KAC among childcare providers