This case report highlights Koro-like symptoms with erectile dysfunction. Methods: We report a case of a Rohingya refugee who presented with Koro-like symptoms associated with erectile dysfunction and severe religious guilt. Results: Sexual dysfunction, i.e. erectile dysfunction may be a predisposing factor for a Koro incidence. Religious issues complicated by superstitious beliefs pose a treatment challenge. Conclusion: Treating patient with sexual dysfunction should involve exploring and addressing patient’s conflicts to avoid worsening of symptoms. As this case illustrates, severe anxiety can present with Koro-like symptoms.