Technology bring possibility to conduct focus groupdiscussion (FGD) virtually, especially during COVID-19. Online FGD conducted to explore needs assessment to design an effective drug prevention program among high-risk youth. 10 Online FGD within 5 participant for each group conducted involving youths from high-risk areas. Sessions recorded with the participants’ consent. Online FGD provides flexibility of time and venue, and widens the opportunity to gather more in-depth data. However, online FGD might cause the interactions less dynamic. Thus, it calls for future studies on the effectiveness of online focus group discussion as compared to the conventional face-to-face method.