Ranking function acts as a predictive algorithm that is used to establish a simple ordering of documents according to its relevance and this process shows the effectiveness, quality and the accuracy for the variety type of Information Retrieval (IR) such as, Domain Specific Retrieval of Malay Translated Hadith. In this research, a Hierarchical Fuzzy Logic Controller of Mamdani-type Fuzzy Inference System has been built to define the ranking function based on the BM25 Model. The model examines four-inputs which are Ontology BM25 Score, Fabrication Rate of Hadith, Shia Rate of Hadith from the previous works of the researchers and the New additional Positive Rate of Hadith. It also examines four-output values of Final Ranking Score which consist of three triangular membership functions. The new Positive Rate of hadith is based on the score value of the automatic text summarization that was executed in pre-processing phase. The proposed system has outperformed the BM25 original score and the Vector Space Model (VM) on 5 topic of queries and 26 queries in the term of individual queries, while the BM25 original score and Vector Space Model only yielded better result in 3 and 0 queries respectively on the P@10, %no measures and MAP. P@10 represent the values of Precision at Rank 10 P@10), %no measures represent the percentage of queries with no relevant documents in the top ten retrieved and MAP represents Mean Average Precision of the queries. The results show the proposed system have capability to demote negative documents and move up the relevant documents in the ranking list with positive indicator and its capability to recall unseen document with the application of ontology in text retrieval. For the future works, the researcher would like to apply the usage of new ranking indicator such as reliability score from the expert and the lay users of the Domain Specific Retrieval of Malay Translated Hadith.

Background aims. The aim of the present study was to evaluate the effects of air-liquid interface on the differentiation potential of human amnion epithelial cells (HAECs) to skin-like substitute in organotypic culture. Methods. HAECs at passage 1-2 were seeded onto a fibrin layer populated with human amnion mesenchymal cells to form the organotypic cultures. The organotypic HAECs were then cultured for 7, 14 and 21 d in two types of culture system: the submerged culture and the air-liquid interface culture. Cell morphogenesis was examined under the light and electron microscopes (transmission and scanning) and analyzed by immunohistochemistry. Results. Organotypic HAECs formed a single layer epithelium after 3 wk in submerged as well as air-liquid interface cultures. Ultrastructurally, desmosomes were observed in organotypic HAECs cultured in the air-liquid interface but not in the submerged culture. The presence of desmosomes marked the onset of early epidermal differentiation. Organotypic HAECs were positive against anti-CK18 and anti-CK14 in both the submerged and the air-liquid interface cultures. The co-expression of CK14 and CK18 suggested that differentiation of HAECs into skin may follow the process of embryonic skin development. However, weak expression of CK14 was observed after 2 and 3 wk of culture in air-liquid interface. CK10, involucrin, type IV collagen and laminin-5 expression was absent in organotypic HAECs. This observation reflects the initial process of embryonic epidermal differentiation and stratification. Conclusions. Results from the present study suggest that the air-liquid interface could stimulate early differentiation of organotypic HAECs to epidermal cells, with a potential use for skin regeneration.

This study focuses on identifying the best site for placement of pulse oximeter probe for accurate measuring of oxygen saturation. Twenty-three healthy male volunteers aged 20 to 40 years old were recruited in this study. Cold pressor test was done to stimulate vasoactivity and 460 measurements of SpO(2) level were obtained throughout the study. The results were analyzed using ANOVA with p < 0.05 was considered to be significant. Bias between sites are determined using Bland-Altman plot whilst the internal consistency of each measurement sites are identified via Cronbach-Alpha (alpha). Results showed that the best site for cutaneous oxygen saturation measurement is at the earlobe using the ear sensor. Portable finger pulse oximeter oxygen saturation estimation is accurate and reliable at specific fingers (thumb, right middle and right ring fingers) regardless of stimulation on peripheral vasoactivity.