A new chain of Schiff base complexes made up of Cu (II), Co (II), Cd (II),Ni (II), and Mn (II) ions derivatives were obtained by the condensation of 4-dimethyl-aminobenzaldehyde, and 4-aminoantipyrin and some amino acids. The structures of all synthesized complexes were established on the basis of their elemental analysis (UV, FTIR, and 1HNMR). The study of X-ray crystallographic shows that the compound (Z)-4-((4-(dimethylamino)benzylidene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (L5) crystallized in monoclinic system with space group of C2/c and the unit cell dimensions are a= 17.7916, b= 6.8610, c= 29.7199, α =90.000 β =101.326 γ = 90.000., Z = 8 and V = 3557.20 Å3.The antibacterial activity of the complexes are tested against Bacillus subtilis, Bacillus cereus and Pseudomonas aeruginosa. Keywords: Schiff base, 4-dimethyl-aminobenzaldehyde, 4-aminoantipyrin, Schiff base complexes, Bacillus cereus, Pseudomonas aeruginosa and Bacillus subtilis.