This study aims to identify the impact of using the Brainology program in developing students' critical thinking, increasing motivation towards learning, and increasing their achievement. The researcher selected a deliberate sample of eighth grade students at an American school in the Gaza Strip - Palestine in the first semester of the 2019 / 2020 school year. To achieve the objectives of the study, the researcher used a quantitative survey methodology. The researcher adopted the Watson Glaser critical thinking test, while motivation for science learning was measured with the Glenn and Kopala (2006) scale. To measure academic achievement. After completing the program, interviews were conducted with a sample of students. For the results of the study, the data was analyzed using the SPSS statistical package, where quantitative survey methodology statistics were used, and mode. Other analyzes such as (Mann-Whitney) and appropriate statistical tests are also used to answer the research questions. The results of the study concluded that the Brainology program provided a statistically significant difference in the motivation domain for the experimental group, but there was no statistically significant difference in the domain of critical thinking and academic achievement. In addition, interviews show clear changes in motivation, persistence, and challenges towards academic tasks.