Islamic revelation as the main reference in the exploration of knowledge has created scientific methods and thoughts based on tawḥīd. This can be seen through scientific discoveries by the legacy of Islamic scholars such as Jabir Ibn Hayyan, al-Khawarizmi, al-Bīrūnī, Ibn Sina, Ibn Qayyim, and many others who integrated the revelation and scientific knowledge to solve the problems faced by mankind. The objectives of this paper are to elaborate the benefits, preconditions and needs of the integration of turath and scientific knowledge as a contemporary da’wah initiative. In other words, scientific knowledge is made as a Manhaj Rabbani in the transformation of da’wah based on tawḥīd. The qualitative method is applied to collect information through the analysis of books, journals, and academic publications. The results of the findings show that the integration of turath and scientific knowledge in multidisciplinary research is very beneficial and serves as the contemporary da’wah medium. At the same time, it also gives confidence to the preacher to speak in multidisciplinary subject matters.