Students Information System (SIS) is considered as an important system in the management and development of higher education institutions. SIS have been widely studied focusing on factors that influences the intention to use and adopt, and the performance of information systems but limited in system quality. Since system quality is essential to encourage user to have the “intention to use” of SIS and bring toward the successful of SIS implementation, the study on influences factors of system quality is an important. This paper aims to identify the factors of system quality, investigate the relationship of intention to use between the system’s quality and user’s satisfaction of SIS. This quantitative study is based on purposive sampling method and uses questionnaire to collect randomly data from 275 postgraduate students in a selected university. Eight (8) relevant factors has been identified from the reviewing the literature. The result shows that intention to use has relationship between system’s quality and user’s satisfaction as output of SIS and affect the frequent users’ level of satisfaction. This study proposes a model of intention to use of SIS that recommend the developers of SIS to give special attention to the development process and focus on the dimensions of SIS quality to enhance the level of usage SIS and particularly influence on user's satisfaction in educational institutions.