Publication:
Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate

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dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversiti Malaysia Sabah (UMS)
dc.contributor.affiliationsUniversiti Putra Malaysia (UPM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsAsia Metropolitan University
dc.contributor.authorSabullah M.K.en_US
dc.contributor.authorAhmad S.A.en_US
dc.contributor.authorShukor M.Y.en_US
dc.contributor.authorGansau A.J.en_US
dc.contributor.authorShamaan N.A.en_US
dc.contributor.authorKhalid A.en_US
dc.contributor.authorSulaiman M.R.en_US
dc.date.accessioned2024-05-28T08:26:00Z
dc.date.available2024-05-28T08:26:00Z
dc.date.issued2017
dc.description.abstractThe environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO 4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO 4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO 4 , the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm 2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. � All Rights Reserved.en_US
dc.description.natureFinalen_US
dc.identifier.epage1320
dc.identifier.issn19854668
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85024089670
dc.identifier.spage1314
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85024089670&partnerID=40&md5=127aaa51866719c4101b921935dcd028
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/8699
dc.identifier.volume24
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherUniversiti Putra Malaysiaen_US
dc.relation.ispartofInternational Food Research Journalen_US
dc.sourceScopus
dc.subjectCopperen_US
dc.subjectHepatocyteen_US
dc.subjectMorphologyen_US
dc.subjectPuntius javanicusen_US
dc.titleAlteration in morphological features of Puntius javanicus liver exposed to copper sulfateen_US
dc.typeArticleen_US
dspace.entity.typePublication

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