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Occult Disseminated Metastatic Breast Carcinoma Presenting As Acquired Thrombotic Thrombocytopenic Purpura

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dc.contributor.authorSiew Lian Chonga,en_US
dc.contributor.authorProf. Madya Dr. Asral Wirda Binti Ahmad Asnawien_US
dc.contributor.authorRoszymah Hamzahen_US
dc.contributor.authorPek Kuen Liewaen_US
dc.contributor.authorTee Chuan Ongen_US
dc.contributor.authorSen Mui Tanen_US
dc.contributor.authorKian Meng Changen_US
dc.date.accessioned2024-05-28T08:43:42Z
dc.date.available2024-05-28T08:43:42Z
dc.date.issued2021
dc.date.submitted2022-1-27
dc.descriptionCase Rep Oncol 2021;14:1814–1820en_US
dc.description.abstractCancer-related microangiopathic hemolytic anemia (MAHA) is a rare and life-threatening condition. We present a patient who had been treated for invasive lobular breast carcinoma in clinical remission with fever and hemolytic anemia. The peripheral blood film showed MAHA and thrombocytopenia, and a functional deficiency of ADAMTS13 activity of 23% consistent with acquired thrombotic thrombocytopenic purpura. Bone marrow aspirate and trephine biopsy confirmed metastatic carcinoma. Further evaluation revealed the involvement of multiple bone sites without recurrence of the primary tumor. The patient received a daily plasma exchange with cryosupernatant and was pulsed with corticosteroids. MAHA related to breast cancer appears to be a rare occurrenceen_US
dc.identifier.citationChong, Siew & Asnawi, Asral & Hamzah, Roszymah & Liew, Pek Kuen & Ong, Tee & Tan, Sen Mui & Chang, Kian. (2021). Occult Disseminated Metastatic Breast Carcinoma Presenting as Acquired Thrombotic Thrombocytopenic Purpura. Case Reports in Oncology. 14. 1814-1820. 10.1159/000521159.en_US
dc.identifier.doi10.1159/000521159
dc.identifier.epage1820
dc.identifier.issn1662-6575
dc.identifier.issue3
dc.identifier.other597-25
dc.identifier.spage1814
dc.identifier.urihttps://www.karger.com/Article/Pdf/521159
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85122325498&origin=resultslist&sort=plf-f&src=s&st1=Occult+Disseminated+Metastatic+Breast+Carcinoma+Presenting+As+Acquired+Thrombotic+Thrombocytopenic+Purpura&sid=7217474b6891f9255d0b58cdb4085fb3&sot=b&sdt=b&sl=121&s=TITLE-ABS-KEY%28Occult+Disseminated+Metastatic+Breast+Carcinoma+Presenting+As+Acquired+Thrombotic+Thrombocytopenic+Purpura%29&relpos=0&citeCnt=0&searchTerm=&featureToggles=FEATURE_NEW_DOC_DETAILS_EXPORT:1,FEATURE_EXPORT_REDESIGN:0
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9358
dc.identifier.volume14
dc.language.isoenen_US
dc.publisherS. Karger AGen_US
dc.relation.ispartofCase Reports in Oncologyen_US
dc.subjectMicroangiopathy · ADAMTS13 · Carcinoma · Thrombotic thrombocytopenic purpura · Hemolysisen_US
dc.titleOccult Disseminated Metastatic Breast Carcinoma Presenting As Acquired Thrombotic Thrombocytopenic Purpuraen_US
dc.typeArticleen_US
dspace.entity.typePublication

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