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Heavy metal biomarker: Fish behavior, cellular alteration, enzymatic reaction and proteomics approaches

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dc.citedby20
dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversiti Putra Malaysia (UPM)
dc.contributor.affiliationsUniversiti Malaysia Sabah (UMS)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorSabullah M.K.en_US
dc.contributor.authorAhmad S.A.en_US
dc.contributor.authorShukor M.Y.en_US
dc.contributor.authorGansau A.J.en_US
dc.contributor.authorSyed M.A.en_US
dc.contributor.authorSulaiman M.R.en_US
dc.contributor.authorShamaan N.A.en_US
dc.date.accessioned2024-05-28T08:26:35Z
dc.date.available2024-05-28T08:26:35Z
dc.date.issued2015
dc.description.abstractDue to the latest industrial development, many dangerous chemicals have been released directly or indirectly which resulted in the polluted water bodies. Water rehabilitation is an alternative way to restore the quality of water, followed by the environmental management to control the waste discharge to ensure the balance of the degradation rates or detoxifying by environmental factors. However, this process consumed a lot of time and cost. Besides, most of the metal ions, especially copper which is capable to bioaccumulate in aquatic organism and at the elevated level may cause physiological and biochemical alteration which leads to mortality. Environmental monitoring is the initial step presupposed evaluating the potential toxicity of effluent gushing at its purpose to discharge, avoiding the determining effects of contaminant in water bodies. Due to the high sensitivity of the aquatic life towards dissolving toxicant, the fish has been utilized as the biological measurement (Biomarker) to indicate the existence of toxicant exposure and/or the impact towards the evaluation of molecular, cellular to physiological level. Thus, this paper gives an overview of the manipulation of fish as a biomarker of heavy metals through behavior response, hepatocyte alteration, enzymatic reaction and proteomic studies which have proven to be very useful in the environmental pollution monitoring. � All Rights Reserved.en_US
dc.identifier.epage454
dc.identifier.issue2
dc.identifier.spage435
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84928733306&partnerID=40&md5=98cd663fa34af9b37e9f759d9aa6fd73
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/8742
dc.identifier.volume22
dc.language.isoen_USen_US
dc.relation.ispartofInternational Food Research Journalen_US
dc.subjectBehavioren_US
dc.subjectCellularen_US
dc.subjectCopperen_US
dc.subjectEnzymeen_US
dc.subjectHeavy metalsen_US
dc.subjectProteomicsen_US
dc.titleHeavy metal biomarker: Fish behavior, cellular alteration, enzymatic reaction and proteomics approachesen_US
dc.typeArticleen_US
dspace.entity.typePublication

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