Publication: Optimization of eugenol ester using statistical approach of response surface methodology
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Date
2016
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Publisher
Trans Tech Publications Ltd
Abstract
In this study, optimization of eugenol caprylate, a type of ester was successfully carried out using statistical approach of Response surface methodology (RSM). The eugenol ester was synthesized via green route of an enzymatic esterification reaction between eugenol and caprylic acid. Four important enzymology parameters were investigated such as reaction time, temperature, molar ratio of substrate and amount of enzyme. High percentage conversion of ester >80% was achieved at reaction time of 240.40 minute, 25.52 mg of enzyme�s amount, 1.13 molar ratio substrate and temperature of 56.57 �C based on the optimum conditions. The efficiency of a new dual enzymes system consisting of Novozym 435 and Lipozyme TL IM was also evaluated based on the effect of heat and its reusability on the esterification reaction. � 2016 Trans Tech Publications, Switzerland.
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Keywords
Dual enzymes system, Enzymatic esterification, Eugenol ester, Optimization, Response surface methodology, Enzymes, Esterification, Optimization, Reusability, Surface properties, Caprylic acid, Dual-enzymes, Enzymatic esterification, Esterification reactions, Lipozyme TL IM, Optimum conditions, Response surface methodology, Statistical approach, Esters