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Phylogenetic analysis of respiratory syncytial virus identified at universiti kebangsaan Malaysia medical centre

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dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversiti Kebangsaan Malaysia (UKM) Medical Centre
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorRahman M.M.en_US
dc.contributor.authorWong K.K.en_US
dc.contributor.authorIsahak I.en_US
dc.contributor.authorRashid Z.Z.en_US
dc.contributor.authorAlfizah H.en_US
dc.date.accessioned2024-05-29T02:01:00Z
dc.date.available2024-05-29T02:01:00Z
dc.date.issued2014
dc.description.abstractHuman respiratory syncytial virus (RSV) is an important cause of acute respiratory tract infection in infants and young children. Phylogenetic analysis for RSV in Malaysia has not been reported before. We investigated the genetic features of RSV in respiratory specimens from March to August 2011 with molecular methods. From a total of 130 throat swab and nasopharyngeal aspirate specimens, 54 (41.5%) were positive with RSV, identified by in-house real-time reverse transcriptase polymerase chain reaction (rRT-PCR) assay. Thirty-four out of 54 (63.0%) RSV positive patients were children below two years old and two (1.4%) were adults. Phylogenetic analysis showed 39 isolates were genotype GA5, 13 genotypes GA2, one genotype GA1 and one genotype GA7. The findings indicated four genotypes of RSV circulating in the country and the predominant genotype is GA5.
dc.description.natureFinalen_US
dc.identifier.epage744
dc.identifier.issn1266039
dc.identifier.issue5
dc.identifier.scopus2-s2.0-84900430985
dc.identifier.spage739
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84900430985&partnerID=40&md5=069ca1a241f14f8ba78d5002d2b75f4d
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10148
dc.identifier.volume43
dc.languageEnglish
dc.language.isoen_US
dc.publisherPenerbit Universiti Kebangsaan Malaysiaen_US
dc.relation.ispartofSains Malaysiana
dc.sourceScopus
dc.subjectGA2en_US
dc.subjectGA5 and GA7en_US
dc.subjectGenotype GA1en_US
dc.subjectPhylogenetic analysisen_US
dc.subjectRespiratory syncytial virusen_US
dc.subjectgenotypeen_US
dc.subjectinfectious diseaseen_US
dc.subjectphylogeneticsen_US
dc.subjectrespiratory diseaseen_US
dc.subjectvirusen_US
dc.subjectMalaysiaen_US
dc.subjectHuman respiratory syncytial virusen_US
dc.subjectRespiratory syncytial virusen_US
dc.subjectRice stripe virusen_US
dc.titlePhylogenetic analysis of respiratory syncytial virus identified at universiti kebangsaan Malaysia medical centre
dc.typeArticleen_US
dspace.entity.typePublication

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