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Effect of Nigella sativa supplementation on human lipids: Systematic review

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dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversiti Teknologi MARA (UiTM)
dc.contributor.affiliationsUniversiti Pertahanan Nasional Malaysia (UPNM)
dc.contributor.affiliationsUniversiti Kebangsaan Malaysia (UKM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsQassim University
dc.contributor.authorAl-Naggar R.A.en_US
dc.contributor.authorOsman M.T.en_US
dc.contributor.authorMohamed I.N.en_US
dc.contributor.authorKhairun Nain Nor Aripinen_US
dc.contributor.authorAbdulghani M.A.en_US
dc.date.accessioned2024-05-28T08:30:24Z
dc.date.available2024-05-28T08:30:24Z
dc.date.issued2017
dc.description.abstractNigella sativa (NS) is widely used in traditional medicine and several studies have been conducted to reveal NS effects on different medical disorders including hyperlipidemia. Since hyperlipidemia is a common risk factor for the development of cardiovascular illness. We evaluated the effects of NS supplementation on lipid profile in clinical trial performed among humans. A search on published studies was done by using databases including Scopus, PubMed, Google Scholar, Thomas Reuters Web of Science, and CINAHIL. Terms searched included "Nigella sativa, Black seed, Black cumin, Triglycerides, Cholesterol, Lipoproteins". Initially 432 articles were extracted. However, four hundred eighteen papers were unrelated, reviews, animal studies, combined and duplicated studies were excluded, and finally only fourteen articles were eligible for this review. After analysing 14 articles including 738 participants from different countries and nations. Results of these clinical trials revealed that Nigella sativa is effective to change the lipid profile significantly in different conditions. This systematic review revealed that Nigella sativa supplementation might be effective in hyperlipidemic control in humans and seems potential target of future drug for hyperlipidemic conditions. � 2017 Redhwan Ahmed Al-Naggar et al.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.7324/JAPS.2017.70432
dc.identifier.epage219
dc.identifier.issn22313354
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85018958041
dc.identifier.spage213
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85018958041&doi=10.7324%2fJAPS.2017.70432&partnerID=40&md5=ba021c9c0d16d8ee7d236f9952a5f363
dc.identifier.urihttps://japsonline.com/abstract.php?article_id=2246
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/8946
dc.identifier.volume7
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherOpen Science Publishers LLP Inc.en_US
dc.relation.ispartofJournal of Applied Pharmaceutical Scienceen_US
dc.sourceScopus
dc.subjectBlack seedsen_US
dc.subjectHuman lipidsen_US
dc.subjectHyperlipidemiaen_US
dc.subjectLipid profileen_US
dc.subjectNigella sativaen_US
dc.titleEffect of Nigella sativa supplementation on human lipids: Systematic reviewen_US
dc.typeArticleen_US
dspace.entity.typePublication

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