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Case Series of Acute Myeloid Leukemia (AML) in Pregnancy – A Single Centre Experience over 5 years Review

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dc.contributor.authorEmily Christine D'Silvaen_US
dc.contributor.authorFann Rui Jeaten_US
dc.contributor.authorLim Kar Koongen_US
dc.contributor.authorJameela Satharen_US
dc.date.accessioned2024-05-30T02:07:45Z
dc.date.available2024-05-30T02:07:45Z
dc.date.issued2023
dc.descriptionVOL. 9 NO. 1 (2023) Page (12-17)en_US
dc.description.abstractAcute Myeloid Leukemia (AML) is a rare condition presenting in pregnancy and still poses a challenge in its management which involves maintaining a balance between maternal and fetal well-being. This study aims to create a local registry for hematological malignancy in pregnancy and to review outcomes of both maternal and fetal outcomes. Twelve pregnancies were identified from 11 patients. 3 pregnancies were terminated upon diagnosis and 1 miscarried. One maternal death prior to decision. Out of the 6 pregnancies continued, 5 received chemotherapy during pregnancy with all successfully achieving complete remission and were delivered at 33-37 weeks gestation. All babies delivered with good Apgar score with 1 reported neonatal death. One fetal anomaly reported in a patient exposed to Decitabine in early pregnancy. Chemotherapy can be safely administered during second or third trimester with delivery planned as close to term as possible. Decitabine should be avoided during pregnancy due to its potential teratogenicity.en_US
dc.identifier.citationD’Silva, E. C., Fann, R. J., Lim, K. K., & Sathar, J. (2023). Case Series of Acute Myeloid Leukemia (AML) in Pregnancy – A Single Centre Experience over 5 years Review. Malaysian Journal of Science Health & Technology, 9(1). https://doi.org/10.33102/mjosht.v9i1.269en_US
dc.identifier.doi10.33102/MJOSHT.V9I1.269
dc.identifier.epage17
dc.identifier.issn2601-0003
dc.identifier.issue1
dc.identifier.spage12
dc.identifier.urihttps://mjosht.usim.edu.my/index.php/mjosht/article/view/269/195
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/15472
dc.identifier.volume9
dc.language.isoen_USen_US
dc.publisherUSIM Pressen_US
dc.relation.ispartofMalaysian Journal of Science, Health & Technology (MJoSHT)en_US
dc.subjectAcute myeloid leukemia, AML, AML in pregnancy, maternal outcome in AML, Fetal outcome in AMLen_US
dc.titleCase Series of Acute Myeloid Leukemia (AML) in Pregnancy – A Single Centre Experience over 5 years Reviewen_US
dc.typeArticleen_US
dspace.entity.typePublication

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