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Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate

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dc.contributor.authorSabullah, MKen_US
dc.contributor.authorAhmad, SAen_US
dc.contributor.authorShukor, MYen_US
dc.contributor.authorGansau, AJen_US
dc.contributor.authorShamaan, NAen_US
dc.contributor.authorKhalid, Aen_US
dc.contributor.authorSulaiman, MRen_US
dc.date.accessioned2024-05-29T02:57:51Z
dc.date.available2024-05-29T02:57:51Z
dc.date.issued2017
dc.description.abstractThe environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4, the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm(2) was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P. javanicus is dependent to the dose exposure. (c) All Rights Reserved
dc.identifier.epage1320
dc.identifier.isbn2231-7546
dc.identifier.issn1985-4668
dc.identifier.issue3
dc.identifier.scopusWOS:000427097900056
dc.identifier.spage1314
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/11660
dc.identifier.volume24
dc.languageEnglish
dc.language.isoen_US
dc.publisherUniv Putra Malaysia Pressen_US
dc.relation.ispartofInternational Food Research Journal
dc.sourceWeb Of Science (ISI)
dc.subjectMorphologyen_US
dc.subjectHepatocyteen_US
dc.subjectCopperen_US
dc.subjectPuntius javanicusen_US
dc.titleAlteration in morphological features of Puntius javanicus liver exposed to copper sulfate
dc.typeArticleen_US
dspace.entity.typePublication

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