Publication:
Development and validation of a new simplified anatomic trauma mortality score

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dc.contributor.authorTan, JHen_US
dc.contributor.authorMohamad, Yen_US
dc.contributor.authorAlwi, RIen_US
dc.contributor.authorTan, CLHen_US
dc.contributor.authorAriffin, ACen_US
dc.contributor.authorJarmin, Ren_US
dc.date.accessioned2024-05-29T03:25:06Z
dc.date.available2024-05-29T03:25:06Z
dc.date.issued2019
dc.descriptionInjury Volume 50, Issue 5, May 2019, Pages 1125-1132en_US
dc.description.abstractBackground: Most trauma mortality prediction scores are complex in nature. GAP (Glasgow Coma Scale, Age, Systolic blood pressure) and mGAP (mechanism, Glasgow Coma Scale, Age, Systolic blood pressure) scores are relatively simple scoring tools. However, these scores were not validated in low and middle income countries including Malaysia and its accuracies are influenced by the fluctuating physiologic parameters. This study aims to develop a relevant simplified anatomic trauma scoring system for the local trauma patients in Malaysia. Method: A total of 3825 trauma patients from 2011 to 2016 were extracted from the Hospital Sultanah Aminah Trauma Surgery Registry. Patients were split into a development sample (n = 2683) and a validation sample (n = 1142). Univariate analysis is applied to identify significant anatomic predictors. These predictors were further analyzed using multivariable logistic regression to develop the new score and compared to existing score systems. The quality of prediction was determined regarding discrimination using sensitivity, specificity and receiver operating characteristic [ROC] curve. Results: Existing simplified score systems (GAP & mGAP) revealed areas under the ROC curve of 0.825 and 0.806. The newly developed HeCLLiP (Head, cervical spine, lung, liver, pelvic fracture) score combines only five anatomic components: injury involving head, cervical spine, lung, liver and pelvic bone. The probabilities of mortality can be estimated by charting the total score points onto a graph chart or using the cut-off value of (>2) with a sensitivity of 79.2 and specificity of 70.6% on the validation dataset. The HeCLLiP score achieved comparable values of 0.802 for the area under the ROC curve in validation samples. Conclusion: HeCLLiP Score is a simplified anatomic score suited to the local Malaysian population with a good predictive ability for trauma mortality. (C) 2019 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.injury.2019.01.027
dc.identifier.epage1132
dc.identifier.isbn1879-0267
dc.identifier.isiWOS:000467538200020
dc.identifier.issn0020-1383
dc.identifier.issue5
dc.identifier.pmid30686543
dc.identifier.scopus2-s2.0-85060352371
dc.identifier.spage1125
dc.identifier.urihttps://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0020138319300270?returnurl=null&referrer=null
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85060352371&doi=10.1016%2fj.injury.2019.01.027&partnerID=40&md5=c526ad5f00409e47e210e08dcdb5d31a
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S0020138319300270?via%3Dihub
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/11864
dc.identifier.volume50
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofInjury-International Journal Of The Care Of The Injureden_US
dc.sourceWeb Of Science (ISI)
dc.subjectMortalityen_US
dc.subjectTrauma severity indicesen_US
dc.subjectTraumaen_US
dc.subjectPrognosisen_US
dc.titleDevelopment and validation of a new simplified anatomic trauma mortality scoreen_US
dc.typeArticleen_US
dspace.entity.typePublication

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