Publication:
A case of CMV infection diagnosed from placenta: Refreshing the classic owl’s eye

dc.contributor.authorNur Syahrina Rahimen_US
dc.contributor.authorNoriah Oen_US
dc.contributor.authorArifah MAen_US
dc.contributor.authorHayati ARen_US
dc.date.accessioned2024-05-28T06:37:42Z
dc.date.available2024-05-28T06:37:42Z
dc.date.issued2012
dc.descriptionPosteren_US
dc.description.abstractIntroduction: CMV (Cytomegalovirus) infection of the placenta may demonstrate the diagnostic viral inclusions and/or placental vilitis. Today, by immunohistochemistry, the CMV infected cells are easily identifi ed without having to scrutinise every villous to look for the inclusions. We might have even forgotten the beatiful nature of the owl’s eye inclusions. We would like to share an ordinary case of congenital CMV infection with these characteristic inclusions. Case: A 25 year old lady, in her second pregnancy presented with an intrauterine fetal death at 27 weeks gestation. There was no history of trauma, abdominal pain or pervaginal bleeding. Her fi rst son was born a year ago and is currently alive and well. The fetal scan shows IUGR (intrauterine growth restriction) with parameters of about 20 weeks gestation. With Prostin induction, she delivered a macerated stillborn. On histology, the placenta shows hydropic villi with scattered large cytomegalic cells with eosinophilic inclusions within the stroma. Some of them display the characteristic owl’s eye inclusions. On immunohistochemical staining, these inclusions are reactive to CMV antibody. Conclusion: CMV infection is one of the commonly occuring intrauterine infections. Recognizing the histopathological features may aid in identifying the cause of intrauterine death as many of these women are asymptomatic.en_US
dc.identifier.citationRahim, Nur & O, Noriah & Arifah, Meisa & Rahman, Hayati. (2012). A Case of CMV Infection Diagnosed from Placenta: Refreshing the Classic Owl’s Eye.en_US
dc.identifier.epage189
dc.identifier.issn0126-8635
dc.identifier.issue2
dc.identifier.spage189
dc.identifier.urihttp://www.mjpath.org.my/2012.2/abstracts-annual-meeting.pdf
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/7403
dc.identifier.volume34
dc.language.isoenen_US
dc.publisherCollege of Pathologists, Academy of Medicine Malaysiaen_US
dc.relation.conferenceConference: The 11TH Annual Scientifi c Meeting of the College of Pathologists, Academy of Medicine MalaysiaAt: The Crowne Plaza Mutiara Hotel, Kuala Lumpur, June 2012en_US
dc.relation.ispartofThe Malaysian Journal of Pathologyen_US
dc.titleA case of CMV infection diagnosed from placenta: Refreshing the classic owl’s eyeen_US
dc.typeArticleen_US
dspace.entity.typePublication

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