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Localized Laryngeal Amylodosis Successful Treatment With Systemic Therapy - A Case Report

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dc.contributor.authorR. Amilahen_US
dc.contributor.authorH. Shahrulen_US
dc.contributor.authorNor Eyzawiah Binti Hassanen_US
dc.contributor.authorA. B. Azreenen_US
dc.date.accessioned2024-05-27T14:44:32Z
dc.date.available2024-05-27T14:44:32Z
dc.date.issued2021
dc.date.submitted2021-11-8
dc.description.abstractAmyloidosis is a rare idiopathic extracellular deposition of an amorphous amyloid substance in tissues which ultimately leads to organ malfunction and failure. Clinically, amyloidosis is divided into 2 categories; systemic and localized. Localized amyloidosis is rare and clinical presentation is variable and often non-specific ranging from simple hoarseness, dysphagia and bleeding to lethal airway obstruction, depending on size and location of the amyloid deposition. The main treatment for laryngeal amyloidosis is by surgical intervention, however medical treatment is an option in certain case. We reported a case of patient presented with hoarseness and been diagnosed as laryngeal amyloidosis. As the patient refused for surgical intervention, he was treated with oral thalidomide. After five years of close follow-up, patient shows improvement with no evidence of disease progression or airway compromise.en_US
dc.identifier.epage4
dc.identifier.issue2
dc.identifier.other1390-19
dc.identifier.spage1
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/3702
dc.identifier.volume5
dc.language.isoenen_US
dc.publisherSCIENCEDOMAIN Internationalen_US
dc.relation.ispartofAsian Journal of Research in Surgeryen_US
dc.subjectHoarseness; laryngeal amyloidosis; thalidomideen_US
dc.titleLocalized Laryngeal Amylodosis Successful Treatment With Systemic Therapy - A Case Reporten_US
dc.typeArticleen_US
dspace.entity.typePublication

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