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Identification of genotypes of Influenza A virus in Malaysia

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dc.contributor.authorRahman, MMen_US
dc.contributor.authorWong, KKen_US
dc.contributor.authorIsahak, Ien_US
dc.contributor.authorRashid, ZZen_US
dc.contributor.authorAlfizah, Hen_US
dc.date.accessioned2024-05-29T02:51:05Z
dc.date.available2024-05-29T02:51:05Z
dc.date.issued2014
dc.description.abstractObjective: Influenza is considered as an emerging disease until today. The present study was undertaken to determine the prevalent genotypes of Influenza A virus in Malaysia. Methods: Influenza A virus was identified from respiratory specimens by real-time reverse transcriptase polymerase chain reaction (rRT-PCR). Phylogenetic analysis of the identified isolates was performed and genotypes were detected. Results: A total number of 505 throat swabs and nasopharyngeal aspirates were examined by rRT-PCR at Universiti Kebangsaan Malaysia Medical Centre (UKMMC) in which 65(12.87%) were positive for influenza A. The identified isolates were successfully genotyped by phylogenetic analysis. The identified influenza A genotypes were: H1N1 (42), H3N2 (20) and H5N1 (3). Conclusion: The findings indicated that 3 genotypes were circulating in Malaysia during 2011 in which H1N1 was the predominant. Results added new genotype (H5N1) identification record in Malaysia that may be added in data base of WHO and CDC.
dc.identifier.epage1071
dc.identifier.issn1682-024X
dc.identifier.issue5
dc.identifier.scopusWOS:000342973000030
dc.identifier.spage1068
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/11151
dc.identifier.volume30
dc.languageEnglish
dc.language.isoen_US
dc.publisherProfessional Medical Publicationsen_US
dc.relation.ispartofPakistan Journal Of Medical Sciences
dc.sourceWeb Of Science (ISI)
dc.subjectInfluenza Aen_US
dc.subjectrRT-PCRen_US
dc.subjectH1 N1en_US
dc.subjectH3N2en_US
dc.subjectH5N1en_US
dc.subjectPhylogenetic analysisen_US
dc.titleIdentification of genotypes of Influenza A virus in Malaysia
dc.typeArticleen_US
dspace.entity.typePublication

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