Publication:
High yield synthesis of kojic ester using dual enzymes system and their antibacterial activity

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dc.Conferencecode101903
dc.Conferencedate28 November 2013 through 29 November 2013
dc.ConferencelocationBandung
dc.Conferencename2013 International Conference on Advanced Materials Engineering and Technology, ICAMET 2013
dc.citedby1
dc.contributor.affiliationsFaculty of Science and Technology
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsUniversiti Putra Malaysia (UPM)
dc.contributor.authorRadzi S.M.en_US
dc.contributor.authorRahman N.J.A.en_US
dc.contributor.authorNoor H.M.en_US
dc.contributor.authorBasri M.en_US
dc.date.accessioned2024-05-29T01:57:09Z
dc.date.available2024-05-29T01:57:09Z
dc.date.issued2014
dc.description.abstractEnzymatic synthesis of kojic ester, a bio-based whitening agent, was successfully carried out via esterification reaction between oleic acid and kojic acid. Commercial immobilized lipases of Novozym 435 and Lipozyme RM IM were used in combination as biocatalyst in the reaction system. Various reaction parameters were chosen to optimize the reaction in order to obtain a high yield of kojic ester including the best ratio of lipases, reaction time and reaction temperature. The optimum conditions for the synthesis of kojic ester was achieved at reaction time of 12 hours, temperature of 60 �C and equal ratio of lipases to produce more than 70 % yield. Antimicrobial tests of synthesized kojic ester towards several types of bacteria via Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) analyses were also examined. The results obtained suggested that kojic ester exhibits a good bactericidal effect towards all bacteria tested such as Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella typhimurium. Copyright � 2014 Trans Tech Publications Ltd, Switzerland.
dc.description.natureFinalen_US
dc.identifier.CODENKEMAE
dc.identifier.doi10.4028/www.scientific.net/KEM.594-595.362
dc.identifier.epage369
dc.identifier.isbn9783040000000
dc.identifier.issn10139826
dc.identifier.scopus2-s2.0-84891875110
dc.identifier.spage362
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84891875110&doi=10.4028%2fwww.scientific.net%2fKEM.594-595.362&partnerID=40&md5=17fa9c94a2d785a8b9031bde9a6875c5
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9904
dc.identifier.volume594-595
dc.languageEnglish
dc.language.isoen_US
dc.relation.ispartofKey Engineering Materials
dc.sourceScopus
dc.subjectAntimicrobial activityen_US
dc.subjectDual enzymes systemen_US
dc.subjectKojic esteren_US
dc.subjectOptimizationen_US
dc.subjectWhitening agenten_US
dc.subjectAnti-bacterial activityen_US
dc.subjectAnti-microbial activityen_US
dc.subjectDual-enzymesen_US
dc.subjectEsterification reactionsen_US
dc.subjectMinimum bactericidal concentration (MBC)en_US
dc.subjectMinimum inhibitory concentrationen_US
dc.subjectSalmonella typhimuriumen_US
dc.subjectWhitening agentsen_US
dc.subjectEnzymesen_US
dc.subjectEscherichia colien_US
dc.subjectEstersen_US
dc.subjectOptimizationen_US
dc.subjectSalmonellaen_US
dc.subjectEsterificationen_US
dc.titleHigh yield synthesis of kojic ester using dual enzymes system and their antibacterial activity
dc.typeConference Paperen_US
dspace.entity.typePublication

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