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Bioactive Protein Produced By Lactobacillus Plantarum ATCC 8014 In The Presence Of Allium Sativum

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dc.contributor.authorlsmatul Nurul Asyikin lsmailen_US
dc.contributor.authorHanina Mohd Nooren_US
dc.contributor.authorHairul Shahril Muhamaden_US
dc.contributor.authorSalina Mat Radzien_US
dc.contributor.authorAbdul Jalil Abdul Kaderen_US
dc.contributor.authorMaryam Mohamed Rehanen_US
dc.contributor.authorRosfarizan Mohameden_US
dc.date.accessioned2024-05-28T04:40:11Z
dc.date.available2024-05-28T04:40:11Z
dc.date.issued2014
dc.descriptionThe 2nd International Symposium and Workshop on Functional Genomics and Structural Biology 21-24 January 2014 Mines Wellness Hotel, Malaysiaen_US
dc.description.abstractSeveral studies have reported that sub inhibitory concentrations of antibiotics or antimicrobials are capable to modulate bacteria transcription processes. Therefore, the bacteria might have introduced new proteins in mild stress surroundings like in the presence of antimicrobial agents at low concentrations. However, there are limited elucidations about unexpected ability of natural antimicrobial compounds to become a signaling agent capable to induce biological functions in bacteria at low concentrations. Thus, this present study aims to e'xplore the proteins production by Lactobacillus plantarum ATCC 8014 in the presence of Allium sativum at sub-minimal inhibitory concentration (sub-MIC). The Minimum Inhibition Concentration (MIC) of A. sativum against L. plantarum was 33.33% from microdilution assay. L. plantarum cells were treated with A. sativum at sub-MIC (0.05 x MIC) in the fermentation process. Three new protein bands (approximate size of 97.83 kD, 53.56 kD and 46.71 kD) were detected by SDS-PAGE profile for the treated bacteria. LC-MSIMS analysis identified 11 possible proteins from the three protein bands expressed in mild stress condition. The proteins showed antimicrobial activity toward several Gram-positive and I Gram-negative bacteria. Hence, L. plantarum ATCC 8014 in mild stress condition with the presence of 0.05 x MIC A. sativum could regulate bioactive proteins production.en_US
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/6035
dc.language.isoen_USen_US
dc.relation.conferenceThe 2"d International Symposium and Workshop on Functional Genomics and Structural Biologyen_US
dc.subjectantimicrobial, transcription, sub-MIC, proteins, Lactobacillus plantarum ATCC 80 14, Allium sativumen_US
dc.titleBioactive Protein Produced By Lactobacillus Plantarum ATCC 8014 In The Presence Of Allium Sativumen_US
dc.typeOtheren_US
dspace.entity.typePublication

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