Publication:
Effect of Circadian Rhythm Disturbance on the Human Musculoskeletal System and the Importance of Nutritional Strategies

dc.contributor.authorNorsham Julianaen_US
dc.contributor.authorLiyana Azmien_US
dc.contributor.authorNadia Mohd Effendyen_US
dc.contributor.authorNur Islami Mohd Fahmi Tengen_US
dc.contributor.authorIzuddin Fahmy Abuen_US
dc.contributor.authorNur Nabilah Abu Bakaren_US
dc.contributor.authorSahar Azmanien_US
dc.contributor.authorNoor Anisah Abu Yaziten_US
dc.contributor.authorSuhaini Kadimanen_US
dc.contributor.authorSrijit Dasen_US
dc.date.accessioned2024-05-29T02:28:55Z
dc.date.available2024-05-29T02:28:55Z
dc.date.issued2023
dc.date.submitted2024-2-6
dc.descriptionVolume 15 Issue 3en_US
dc.description.abstractThe circadian system in the human body responds to daily environmental changes to optimise behaviour according to the biological clock and also influences various physiological processes. The suprachiasmatic nuclei are located in the anterior hypothalamus of the brain, and they synchronise to the 24 h light/dark cycle. Human physiological functions are highly dependent on the regulation of the internal circadian clock. Skeletal muscles comprise the largest collection of peripheral clocks in the human body. Both central and peripheral clocks regulate the interaction between the musculoskeletal system and energy metabolism. The skeletal muscle circadian clock plays a vital role in lipid and glucose metabolism. The pathogenesis of osteoporosis is related to an alteration in the circadian rhythm. In the present review, we discuss the disturbance of the circadian rhythm and its resultant effect on the musculoskeletal system. We also discuss the nutritional strategies that are potentially effective in maintaining the system’s homeostasis. Active collaborations between nutritionists and physiologists in the field of chronobiological and chrononutrition will further clarify these interactions. This review may be necessary for successful interventions in reducing morbidity and mortality resulting from musculoskeletal disturbances.en_US
dc.identifier.citationJuliana, N.; Azmi, L.; Effendy, N.M.; Mohd Fahmi Teng, N.I.; Abu, I.F.; Abu Bakar, N.N.; Azmani, S.; Yazit, N.A.A.; Kadiman, S.; Das, S. Effect of Circadian Rhythm Disturbance on the Human Musculoskeletal System and the Importance of Nutritional Strategies. Nutrients 2023, 15, 734. https:// doi.org/10.3390/nu15030734en_US
dc.identifier.doihttps://doi.org/10.3390/nu15030734
dc.identifier.epage753
dc.identifier.issn2072-6643
dc.identifier.issue3
dc.identifier.spage734
dc.identifier.urihttps://www.mdpi.com/2072-6643/15/3/734
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85147807325&origin=resultslist&sort=plf-f&src=s&sid=003cf8cb9c8df919bf8dcf1022647892&sot=b&sdt=b&s=TITLE-ABS-KEY%28Effect+of+Circadian+Rhythm+Disturbance+on+the+Human+Musculoskeletal+System+and+the+Importance+of+Nutritional+Strategies%29&sl=134&sessionSearchId=003cf8cb9c8df919bf8dcf1022647892&relpos=0
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10788
dc.identifier.volume15
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.relation.ispartofNutrientsen_US
dc.subjectchrononutrition; biological clock; circadian; skeletal muscle; metabolismen_US
dc.titleEffect of Circadian Rhythm Disturbance on the Human Musculoskeletal System and the Importance of Nutritional Strategiesen_US
dc.typeArticleen_US
dspace.entity.typePublication

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