Publication:
Anti-proliferative effect of Trigona honey on MCF-7

Simple item page
dc.contributor.authorAbd Rahman Hayatien_US
dc.contributor.authorMasniza Muhamad Lasimen_US
dc.contributor.authorNur Syahrina Binti Rahimen_US
dc.contributor.authorAsral Wirda Ahmad Asnawien_US
dc.contributor.authorMohamed Adel MAR Elkadien_US
dc.contributor.authorNur Fariha Mohd Manzoren_US
dc.date.accessioned2024-05-28T04:23:19Z
dc.date.available2024-05-28T04:23:19Z
dc.date.issued2016
dc.descriptionThe 15th Annual Scientific Meeting of the College of Pathologists, Academy ofMedicine Malaysia was held at Pullman Putrajaya Lakeside Hotel, Putrajaya,Malaysia on 3-5 June 2016 Volume:38 No: 2en_US
dc.description.abstractIntroduction: The ability to proliferate progressively is a crucial characteristic of cancer cells. A number of natural products including prophetic food were demonstrated to have an anti-proliferative effect on cancer cells. Trigona honey has received much attention for its anti-microbial and anti-oxidant properties. The anti-proliferative effect of this honey on cancer cells however, is yet to be discovered. Objective: The aim of this study is to investigate the anti-proliferative effect of Trigona honey on MCF-7 cells. Materials & Methods: MCF-7 cells were cultured in basal medium DMEM-F12, containing 10% fetal bovine serum, 1% antibiotic antimycotic and 1% glutamax. Upon 80% confluence in 96 well plate, used media were replaced with basal media enriched with different concentrations (v/v) of Trigona itama honey; 0, 0.049, 0.195, 0.78, 3.125, 12.5 and 25. Proliferation of MCF-7 cells after 24 and 72 hours were measured by WST assay. Higher absorbance reading denotes higher proliferation rate. Results: MCF-7 cells treated with Trigona honey-enriched media showed consistent reduction in cell proliferation after 24 and 72 hours. Discussion & Conclusion: These preliminary findings show a promising effect of Trigona honey as an anti-cancer agent through its anti-proliferative effect.en_US
dc.identifier.citationRahman, Hayati & Masniza, M.L. & Rahim, Nur & Asnawi, Asral & Elkadi, Mohamed & Mohd Manzor, Fariha. (2016). Anti-proliferative effect of Trigona honey on MCF-7.en_US
dc.identifier.epage206
dc.identifier.issn0126-8635
dc.identifier.issue2
dc.identifier.spage206
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/5482
dc.identifier.volume38
dc.language.isoenen_US
dc.publisherCollege of Pathologistsen_US
dc.relation.ispartofMalaysian Journal of Pathologyen_US
dc.titleAnti-proliferative effect of Trigona honey on MCF-7en_US
dc.typeArticleen_US
dspace.entity.typePublication

Files

Collections

Other Publications