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Anaemia among primary care patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD): A multicentred cross-sectional study

dc.FundingDetailsFunding This study was led and sponsored by the Family Medicine Specialists� Association (FMSA) of Malaysia supported by an unrestricted grant from Roche Malaysia. Veras Research Sdn Bhd was the Contract Research Organization (CRO) appointed by the FMSA to support the design and implementation of the study.
dc.citedby3
dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsKlinik Kesihatan Ampangan
dc.contributor.affiliationsUniversiti Kebangsaan Malaysia (UKM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsKlinik Kesihatan Lukut
dc.contributor.affiliationsKlinik Kesihatan Masjid Tanah
dc.contributor.affiliationsKlinik Kesihatan Bandar Seri Putra
dc.contributor.affiliationsKlinik Kesihatan Batu 13
dc.contributor.authorIdris I.en_US
dc.contributor.authorTohid H.en_US
dc.contributor.authorMuhammad N.A.en_US
dc.contributor.authorRashid M.R.A.en_US
dc.contributor.authorAhad A.M.en_US
dc.contributor.authorAli N.en_US
dc.contributor.authorSharifuddin N.en_US
dc.contributor.authorAris J.H.en_US
dc.date.accessioned2024-05-28T08:29:47Z
dc.date.available2024-05-28T08:29:47Z
dc.date.issued2018
dc.description.abstractObjectives This study aimed to determine the prevalence of anaemia among patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) at primary care settings and its associated factors. Design, setting and participants This cross-sectional study involved 808 adult patients with T2DM and CKD who were recruited via systematic sampling from 20 public primary care clinics in Peninsular Malaysia. Their sociodemographic, clinical and biomedical profiles were collected through interviews, examination of medical records and blood testing. Results The prevalence of anaemia was 31.7% (256/808). The anaemia was mainly mild (61.5%) and normocytic normochromic (58.7%). About 88.7% of the patients with anaemia were not known to have anaemia prior to the study. Among 36 patients with documented history of anaemia, 80.6% were still anaemic, and only a half received iron therapy. Multivariate regression analysis showed that women (adjusted odd ratio (AOR): 1.57, 95% CI: 1.12 to 2.21, p=0.009) and those with older age (AOR: 1.04, 95% CI: 1.01 to 1.06, p<0.001), CKD stage 3a (AOR: 2.47; 95% CI: 1.25 to 4.87, p=0.009), CKD stage 3b (AOR: 4.36; 95% CI: 2.14 to 8.85, p<0.001), CKD stage 4 (AOR: 10.12; 95% CI: 4.36 to 23.47, p<0.001), CKD stage 5 (AOR: 10.80; 95% CI: 3.32 to 35.11, p<0.001) and foot complication (AOR 3.12, 95% CI: 1.51 to 6.46, p=0.002) were more likely to have anaemia. Having higher body mass index (AOR 0.95, 95% CI: 0.92 to 0.99, p=0.012) and higher diastolic blood pressure (AOR 0.97, 95% CI: 0.95 to 0.99, p<0.001) were associated with lower odds to have anaemia. Conclusion Anaemia among patients with T2DM and CKD in primary care was common, and the majority was unrecognised. Inadequate treatment of anaemia was also prevalent. Therefore, screening of anaemia should be incorporated into the routine assessment of diabetic complications particularly for those with significant associated factors. It is hoped that such strategy could lead to early treatment and hence improve their overall care.en_US
dc.description.natureFinalen_US
dc.identifier.ArtNoe025125
dc.identifier.doi10.1136/bmjopen-2018-025125
dc.identifier.issn20446055
dc.identifier.issue12
dc.identifier.pmid30580276
dc.identifier.scopus2-s2.0-85058913556
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85058913556&doi=10.1136%2fbmjopen-2018-025125&partnerID=40&md5=7e4b8059b990034d1fbb7f569d35e92a
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/8918
dc.identifier.volume8
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.ispartofOpen Accessen_US
dc.relation.ispartofBMJ Open
dc.sourceScopus
dc.subjectanaemiaen_US
dc.subjectchronic kidney diseaseen_US
dc.subjectdiabetes mellitusen_US
dc.titleAnaemia among primary care patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD): A multicentred cross-sectional studyen_US
dc.title.alternativeBMJ Openen_US
dc.typeArticleen_US
dspace.entity.typePublication

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