Publication:
Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Review

Simple item page
dc.contributor.authorNur Aqilah Kamaruddinen_US
dc.contributor.authorMuhammad Nazrul Hakim Abdullahen_US
dc.contributor.authorJun Jie Tanen_US
dc.contributor.authorVuanghao Limen_US
dc.contributor.authorLai Yen Fongen_US
dc.contributor.authorSiti Aisyah Abd Ghafaren_US
dc.contributor.authorYoke Keong Yongen_US
dc.date.accessioned2024-05-28T05:58:47Z
dc.date.available2024-05-28T05:58:47Z
dc.date.issued2022
dc.date.submitted2022-7-26
dc.descriptionHindawi Evidence-Based Complementary and Alternative Medicine Volume 2022, Article ID 3311228, 17 pagesen_US
dc.description.abstractVascular endothelial dysfunction is characterized by an imbalance of vasodilation and vasoconstriction, deficiency of nitric oxide (NO) bioavailability and elevated reactive oxygen species (ROS), and proinflammatory factors. This dysfunction is a key to the early pathological development of major cardiovascular diseases including hypertension, atherosclerosis, and diabetes. Therefore, modulation of the vascular endothelium is considered an important therapeutic strategy to maintain the health of the cardiovascular system. Epidemiological studies have shown that regular consumption of medicinal plants, fruits, and vegetables promotes vascular health, lowering the risk of cardiovascular diseases. This is mainly attributed to the phytochemical compounds contained in these resources. Various databases, including Google Scholar, MEDLINE, PubMed, and the Directory of Open Access Journals, were searched to identify studies demonstrating the vascular protective effects of phytochemical compounds. The literature had revealed abundant data on phytochemical compounds protecting and improving the vascular system. Of the numerous compounds reported, curcumin, resveratrol, cyanidin-3-glucoside, berberine, epigallocatechin-3-gallate, and quercetin are discussed in this review to provide recent information on their vascular protective mechanisms in vivo and in vitro. Phytochemical compounds are promising therapeutic agents for vascular dysfunction due to their antioxidative mechanisms. However, future human studies will be necessary to confirm the clinical effects of these vascular protective mechanisms.en_US
dc.identifier.doi10.1155/2022/3311228
dc.identifier.epage17
dc.identifier.issn1741-427X
dc.identifier.issueNA
dc.identifier.other1815-24
dc.identifier.spage1
dc.identifier.urihttps://www.hindawi.com/journals/ecam/2022/3311228/
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/6898
dc.identifier.volume2022
dc.language.isoenen_US
dc.publisherHindawien_US
dc.relation.ispartofEvidence-Based Complementary and Alternative Medicineen_US
dc.titleVascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Reviewen_US
dc.typeArticleen_US
dspace.entity.typePublication

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds; A Review.pdf
Size:
1.75 MB
Format:
Adobe Portable Document Format
Download

Collections

Other Publications