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Antibacterial effect of Pylantus niruri L. (Meniran) from Indonesia toward Staphylococcus epidermidis and Phytochemical Screening
Journal
Research Journal of Pharmacy and Technology
ISSN
0974-360X
0974-3618
Date Issued
2025-09-05
Author(s)
Em Sutrisna
Sri Wahyuni
Devi Usdiana R
Nazefah Abd Hamid
Dzulfadli Rosli
DOI
10.52711/0974-360X.2025.00642
Abstract
<jats:p>Background: In Indonesia there is no antibacterial medicine based on Indonesian medicinal plants Pylantus niruri L. (Meniran) is allegedly to have an antibacterial effect. Objective: This study aims to explore the antibacterial effects of the 96% ethanolic extract of P.niruri and to determine it’s TLC [Thin layer chromatography] Methods: The test design is an invitro study with diffusion and well methods. Bacteria used is S.epidermidis. The plant also performed phytochemical screening to determine the plant content that was suspected to have an antibacterial effect and continued thin layer chromatography. Results: The 96% ethanolic extract of P.niruri at concentrations of 100; 50; 25; 12.5 and 6,125% have an antibacterial effect with inhibition zones of 12,5;18,41; 12,31; 11,09 and 8,83mm. Conclusion: P niruri L. has potency antibacterial toward S. epidermidis</jats:p>
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