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A Rapid Review of Potential Drug Treatments for Children with COVID-19

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dc.contributor.authorKhairun Nain Nor Aripinen_US
dc.contributor.authorMuhammad Yusoff Mohd Ramdzanen_US
dc.contributor.authorJamil Aiman Mohd Baharudinen_US
dc.date.accessioned2024-05-30T02:07:22Z
dc.date.available2024-05-30T02:07:22Z
dc.date.issued2020
dc.date.submitted2021-2-5
dc.description.abstractThe paediatric population constitutes a much smaller proportion of COVID-19 patients and seems to be less severely affected. However, the massive numbers of COVID-19 infections mean that many children require treatment in hospital. In the concerted and wide-ranging effort to discover a safe and effective treatment for COVID-19, paediatric involvement is necessary. This review aims to identify leading potential drug treatments and vaccines for COVID-19 that are being investigated with children involved. Clinicaltrials.gov, WHO Trial Registry Platform (ICTRP) and RAPS COVID-19 vaccine tracker webportals were searched for clinical trials in phase 3 that involved children below 15 years of age. Any preliminary results released were searched online. The review found 25 phase 3 drug trials with paediatric participants and 2 vaccine trials. No preliminary findings were found. Remdesivir appears to be a leading candidate drug treatment and 2 vaccines candidates, inactivated nCoV-19 (Sinopharm) and ChAdOx1 (Oxford University), are recruiting children in large phase 3 trials. No treatments are currently licensed for COVID-19 but results from numerous trials are eagerly awaited.en_US
dc.identifier.citationNor Aripin, K. N., Mohd Ramdzan, M. Y., & Mohd Baharudin, J. A. (2021). A Rapid Review of Potential Drug Treatments for Children with COVID-19. Malaysian Journal of Science Health & Technology, 6(Special Issue). https://doi.org/10.33102/mjosht.v6i.123en_US
dc.identifier.doi10.33102/mjosht.v6i.123
dc.identifier.epage38
dc.identifier.issn2601-0003
dc.identifier.issueSpecial Issue
dc.identifier.spage34
dc.identifier.urihttps://mjosht.usim.edu.my/index.php/mjosht/article/view/123
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/15432
dc.identifier.volume6
dc.language.isoen_USen_US
dc.publisherUniversiti Sains Islam Malaysiaen_US
dc.relation.ispartofMALAYSIAN JOURNAL OF SCIENCE HEALTH & TECHNOLOGYen_US
dc.subjectCOVID-19, child, paediatric, clinical trials, drugs, vaccinesen_US
dc.titleA Rapid Review of Potential Drug Treatments for Children with COVID-19en_US
dc.typeArticleen_US
dspace.entity.typePublication

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