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Phage display antibodies for diagnostic applications

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dc.Chemicals/CASRecombinant Proteins; Single-Chain Antibodies
dc.FundingDetails1001/PSKBP/8630015,�311/CIPPM/44001005 Ministry of Higher Education, Malaysia
dc.FundingDetailsThe authors would like to acknowledge support by the Malaysian Ministry of Higher Education through the Higher Institution Centre of Excellence (HICoE) Grant (Grant No. 311/CIPPM/44001005 ) and Research University Cluster Grant (Grant No. 1001/PSKBP/8630015 ).
dc.citedby31
dc.contributor.affiliationsUniversiti Sains Malaysia (USM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorHairul Bahara N.H.en_US
dc.contributor.authorTye G.J.en_US
dc.contributor.authorChoong Y.S.en_US
dc.contributor.authorOng E.B.B.en_US
dc.contributor.authorIsmail A.en_US
dc.contributor.authorLim T.S.en_US
dc.date.accessioned2024-05-29T01:58:40Z
dc.date.available2024-05-29T01:58:40Z
dc.date.issued2013
dc.description.abstractWith major developments in molecular biology, numerous display technologies have been successfully introduced for recombinant antibody production. Even so, phage display still remains the gold standard for recombinant antibody production. Its success is mainly attributed to the robust nature of phage particles allowing for automation and adaptation to modifications. The generation of monospecific binders provides a vital tool for diagnostics at a lower cost and higher efficiency. The flexibility to modify recombinant antibodies allows great applicability to various platforms for use. This review presents phage display technology, application and modifications of recombinant antibodies for diagnostics. � 2013 The International Alliance for Biological Standardization.
dc.description.natureFinalen_US
dc.identifier.CODENBILSE
dc.identifier.doi10.1016/j.biologicals.2013.04.001
dc.identifier.epage216
dc.identifier.issn10451056
dc.identifier.issue4
dc.identifier.pmid23647952
dc.identifier.scopus2-s2.0-84881219139
dc.identifier.spage209
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84881219139&doi=10.1016%2fj.biologicals.2013.04.001&partnerID=40&md5=cf0b64b4233e03ebe345abb148145267
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10014
dc.identifier.volume41
dc.languageEnglish
dc.language.isoen_USen_US
dc.relation.ispartofBiologicals
dc.sourceScopus
dc.subjectAntibodiesen_US
dc.subjectDiagnosticsen_US
dc.subjectPhage displayen_US
dc.subjectScFven_US
dc.subjectmonoclonal antibodyen_US
dc.subjectrecombinant antibodyen_US
dc.subjectadaptationen_US
dc.subjectantibody affinityen_US
dc.subjectantibody libraryen_US
dc.subjectantibody productionen_US
dc.subjectautomationen_US
dc.subjectbacteriophageen_US
dc.subjectbiopanningen_US
dc.subjectcosten_US
dc.subjectdiagnostic procedureen_US
dc.subjecthybridomaen_US
dc.subjectmolecular biologyen_US
dc.subjectphage displayen_US
dc.subjectpriority journalen_US
dc.subjectproductivityen_US
dc.titlePhage display antibodies for diagnostic applicationsen_US
dspace.entity.typePublication

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