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The remarkable three-dimensional network structure of bacterial cellulose for tissue engineering applications

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dc.Chemicals/CASalkaline phosphatase, 9001-78-9; cellulose, 61991-22-8, 68073-05-2, 9004-34-6; water, 7732-18-5
dc.citedby2
dc.contributor.affiliationsFaculty of Dentistry
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsUniversiti Kebangsaan Malaysia (UKM)
dc.contributor.affiliationsTrieste University
dc.contributor.authorNadia Haliben_US
dc.contributor.authorIshak Ahmaden_US
dc.contributor.authorMario Grassien_US
dc.contributor.authorGabriele Grassien_US
dc.date.accessioned2024-05-28T08:37:46Z
dc.date.available2024-05-28T08:37:46Z
dc.date.issued2019
dc.descriptionInternational Journal of Pharmaceutics Volume 566, 20 July 2019, Pages 631-640en_US
dc.description.abstractCellulose is a natural homopolymer, composed of ?-1,4- anhydro-D-glucopyranose units. Unlike plant cellulose, bacterial cellulose (BC), obtained from species belonging to the genera of Acetobacter, Rhizobium, Agrobacterium, and Sarcina through various cultivation methods and techniques, is produced in its pure form. BC is produced in the form of gel-like, never dry sheet with tremendous mechanical properties. Containing up to 99% of water, BC hydrogel is considered biocompatible thus finding robust applications in the health industry. Moreover, BC three-dimensional structure closely resembles the extracellular matrix (ECM) of living tissue. In this review, we focus on the porous BC morphology particularly suited to host oxygen and nutrients thus providing conducive environment for cell growth and proliferation. The remarkable BC porous morphology makes this biological material a promising templet for the generation of 3D tissue culture and possibly for tissue-engineered scaffolds. � 2019 Elsevier B.V.en_US
dc.description.natureFinalen_US
dc.identifier.CODENIJPHD
dc.identifier.doi10.1016/j.ijpharm.2019.06.017
dc.identifier.epage640
dc.identifier.issn3785173
dc.identifier.pmid31195074
dc.identifier.scopus2-s2.0-85067280911
dc.identifier.spage631
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85067280911&doi=10.1016%2fj.ijpharm.2019.06.017&partnerID=40&md5=b0baadcff720d65acf79393daeb515e4
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S0378517319304612?via%3Dihub
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9195
dc.identifier.volume566
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofInternational Journal of Pharmaceuticsen_US
dc.sourceScopus
dc.subject3D tissue cultureen_US
dc.subjectBacterial celluloseen_US
dc.subjectExtracellular matrixen_US
dc.subjectTissue scaffoldsen_US
dc.titleThe remarkable three-dimensional network structure of bacterial cellulose for tissue engineering applicationsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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