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A Case Report Of Oral Ulcer In Rheumatoid Arthritis: A Diagnostic And Management Dilemma

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dc.contributor.authorSiti Asmat Md Arepen
dc.contributor.authorDinie Qistina Rajalie
dc.contributor.authorAzreen Zaira Abu Bakar
dc.contributor.authorNor Azirah Salahuddin
dc.contributor.authorNour Hanan Daniah Mohd Bakhit
dc.contributor.authorAhmad Anwaar Muhammad Saifullah
dc.contributor.authorNor Eyzawiah Hassan
dc.date.accessioned2024-06-16T06:39:16Z
dc.date.available2024-06-16T06:39:16Z
dc.date.issued2023
dc.date.submitted2024-1-9
dc.descriptionMalaysian Journal of Medicine and Health Sciences Volume 19 Issue (SUPP19) Page (31-33)
dc.description.abstractChronic oral ulcer in patients with rheumatoid arthritis is a diagnostic challenge in primary health care. The possible causes include the disease itself, side effect of treatment, malignancy and infections. This is a case of a 63-year-old woman with underlying rheumatoid arthritis presented with chronic solitary oral ulcer. She was on oral methotrexate (MTX) and high dose folic acid for five years with good compliance. Tissue biopsy showed marked inflammatory cells infiltration and nuclear hyperchromatism with no evidence of malignancy nor infection. The ulcer was resolved after completing antifungal treatment for six weeks following failure of improvement after empirical antibiotic, elimination of possible trauma and discontinuation of MTX. The fungal staining was negative. There are possibilities of false negative results, thus broadened diagnosis with repeated and further investigations are recommended in cases who did not respond to conventional treatment.
dc.identifier.citationSiti Asmat Md Arepen, Dinie Qistina Rajalie, Abu, Z., Nor Azirah Salahuddin, Nour, Anwaar, A., & Nor Eyzawiah Hassan. (2023). A Case Report of Oral Ulcer in Rheumatoid Arthritis: A Diagnostic and Management Dilemma. Malaysian Journal of Medicine and Health Sciences/Malaysian Journal of Medicine and Health Sciences, 19(s19), 31–33. https://doi.org/10.47836/mjmhs.19.s19.9
dc.identifier.doi10.47836/mjmhs.19.s19.9
dc.identifier.epage33
dc.identifier.issn2636-9346
dc.identifier.issueSUPP19
dc.identifier.other2327-11
dc.identifier.spage31
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/20071
dc.identifier.volume19
dc.language.isoen_US
dc.publisherUniversiti Putra Malaysia; Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia
dc.relation.ispartofMalaysian Journal of Medicine and Health Sciences
dc.relation.issn2636-9346
dc.relation.journalMalaysian Journal of Medicine and Health Sciences
dc.subjectOral ulcer
dc.subjectrheumatoid arthritis
dc.subjectmethotrexate
dc.subjectautoimmune disease
dc.subjectimmunocompromised patient
dc.titleA Case Report Of Oral Ulcer In Rheumatoid Arthritis: A Diagnostic And Management Dilemma
dc.typetext::journal::journal article
dspace.entity.typePublication
oaire.citation.endPage33
oaire.citation.issuesupp (19)
oaire.citation.startPage31
oaire.citation.volume19
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