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Prevalence of iron deficiency anaemia and thalassaemia trait among undergraduate medical students

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dc.Chemicals/CASedetic acid, 150-43-6, 60-00-4; hemoglobin, 9008-02-0; iron, 14093-02-8, 53858-86-9, 7439-89-6
dc.citedby4
dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsUniversiti Kebangsaan Malaysia (UKM)
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorAzma R.Z.en_US
dc.contributor.authorAinoon O.en_US
dc.contributor.authorAzlin I.en_US
dc.contributor.authorHamenuddin H.en_US
dc.contributor.authorHadi N.A.en_US
dc.contributor.authorTatt W.K.en_US
dc.contributor.authorSyazana I.N.en_US
dc.contributor.authorAsmaliza A.M.en_US
dc.contributor.authorDas S.en_US
dc.contributor.authorHamidah N.H.en_US
dc.date.accessioned2024-05-29T01:55:09Z
dc.date.available2024-05-29T01:55:09Z
dc.date.issued2012
dc.description.abstractBackground. Anaemia is a global health problem including Malaysia. In adults, anaemia may affect work productivity. Iron deficiency anaemia and thalassaemia are common causes of anaemia in Malaysia. However, there is scarcity of data on national prevalence of iron deficiency anaemia and thalassaemia, especially in young adults. This cross sectional study was performed to determine the prevalence of iron deficiency anaemia and thalassaemia among medical students of Universiti Kebangsaan Malaysia Medical Centre (UKMMC). Materials and Methods. Blood samples collected in EDTA tubes were analyzed for haemoglobin level and red cell parameters such as MCV, MCH and red cell counts. Samples with abnormal red cell indices were sent for analysis of RBC morphology, iron status, haemoglobin analysis and DNA analysis. Results. A total of 400 samples were available for this study. Fiftyeight (14.5%) students had hypochromic microcytic red cell indices in which 44 (11%) showed thalassaemia red cell indices while 14 (3.5%) had iron deficiency red cell indices which were finally confirmed by serum iron/TIBC analysis. Amongst those suspected to have thalassaemia, 12 (27.3%) were confirmed as alpha thalassaemia trait (??/--SEA), 11 (25%) as Haemoglobin-E trait, 8 (18.2%) as beta thalassaemia trait and 2 (4.5%) as Haemoglobin Constant Spring (??/?CS?). However, eleven students (25%) with thalassaemia red cell indices could not be confirmed with the common thalassaemia primers available, thus causes have yet to be established. Conclusion. Our prevalence of thalassaemia was high and thus we opine that better screening methods should be adopted. � Societ� Editrice Universo (SEU).en_US
dc.description.natureFinalen_US
dc.identifier.CODENCLTEA
dc.identifier.epage291
dc.identifier.issn99074
dc.identifier.issue4
dc.identifier.pmid23007811
dc.identifier.scopus2-s2.0-84867348606
dc.identifier.spage287
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84867348606&partnerID=40&md5=4e6fb7d7709bb2a4571832293f3b7201
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9642
dc.identifier.volume163
dc.languageEnglish
dc.language.isoen_USen_US
dc.relation.ispartofClinica Terapeutica
dc.sourceScopus
dc.subjectAnaemiaen_US
dc.subjectIron deficiencyen_US
dc.subjectMedicalen_US
dc.subjectStudentsen_US
dc.subjectThalassaemiaen_US
dc.subjectTraiten_US
dc.titlePrevalence of iron deficiency anaemia and thalassaemia trait among undergraduate medical studentsen_US
dc.title.alternativeClin. Ter.en_US
dc.typeArticleen_US
dspace.entity.typePublication

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