Publication:
High Yield Synthesis of Kojic Ester using Dual Enzymes System and Their Antibacterial Activity

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dc.ConferencecodeCtr Excellence Geopolymer & Green Technol, Univ Malaysia Perlis, Sch Mat Engn
dc.ConferencedateNOV 28-29, 2013
dc.ConferencelocationBandung, INDONESIA
dc.ConferencenameInternational Conference on Advanced Materials Engineering and Technology (ICAMET 2013)
dc.contributor.authorRadzi, SMen_US
dc.contributor.authorRahman, NJAen_US
dc.contributor.authorNoor, HMen_US
dc.contributor.authorBasri, Men_US
dc.date.accessioned2024-05-29T02:49:37Z
dc.date.available2024-05-29T02:49:37Z
dc.date.issued2014
dc.description.abstractEnzymatic synthesis of kojic ester, a bio-based whitening agent, was successfully carried out via esterification reaction between oleic acid and kojic acid. Commercial immobilized lipases of Novozym 435 and Lipozyme RIM FM were used in combination as biocatalyst in the reaction system. Various reaction parameters were chosen to optimize the reaction in order to obtain a high yield of kojic ester including the best ratio of lipases, reaction time and reaction temperature. The optimum conditions for the synthesis of kojic ester was achieved at reaction time of 12 hours, temperature of 60 degrees C and equal ratio of lipases to produce more than 70 % yield. Antimicrobial tests of synthesized kojic ester towards several types of bacteria via Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) analyses were also examined. The results obtained suggested that kojic ester exhibits a good bactericidal effect towards all bacteria tested such as Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella typhimurium.
dc.identifier.doi10.4028/www.scientific.net/KEM.594-595.362
dc.identifier.epage+
dc.identifier.issn1013-9826
dc.identifier.scopusWOS:000336337200066
dc.identifier.spage362
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10887
dc.identifier.volume594-595
dc.languageEnglish
dc.language.isoen_US
dc.publisherTrans Tech Publications Ltden_US
dc.relation.ispartofAdvanced Materials Engineering And Technology Ii
dc.sourceWeb Of Science (ISI)
dc.subjectKojic esteren_US
dc.subjectdual enzymes systemen_US
dc.subjectwhitening agenten_US
dc.subjectantimicrobial activityen_US
dc.subjectoptimizationen_US
dc.titleHigh Yield Synthesis of Kojic Ester using Dual Enzymes System and Their Antibacterial Activity
dc.typeProceedings Paperen_US
dspace.entity.typePublication

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