Publication: Refining The Mechanism Of Drug-influenced Gingival Enlargement
Loading...
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Cureus
Abstract
Drug-influenced gingival enlargement (DIGE) or overgrowth manifests as abnormal enlargement of the gingiva due to an adverse effect of certain drug reactions in patients treated with anticonvulsants, immunosuppressants, or calcium channel blockers (CCBs). As the gingival enlargement became significant, it may interfere with the normal oral hygiene measures, aesthetics, as well as masticatory functions of the patients. The exact mechanism of how this undesirable condition develops is yet unknown, and complicated, with non-inflammatory and inflammatory pathways involved. This review illuminates these putative pathways of DIGE and highlights various treatment approaches based on existing research and current observations.
Description
Keywords
immunosuppressants, anticonvulsants, calcium channel blockers, drug- influenced gingival enlargement, gingival enlargement
Citation
Sabarudin M, Taib H, Wan Mohamad W (May 15, 2022) Refining the Mechanism of Drug-Influenced Gingival Enlargement and Its Management. Cureus 14(5): e25009. doi:10.7759/cureus.25009