Publication: Fabrication of interdigitated high-performance zinc oxide nanowire modified electrodes for glucose sensing
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Diabetes is a metabolic disease with a prolonged elevated level of glucose in the blood leads to long-term complications and increases the chances for cardiovascular diseases. The present study describes the fabrication of a ZnO nanowire (NW)-modified interdigitated electrode (IDE) to monitor the level of blood glucose. A silver IDE was generated by wet etching-assisted conventional lithography, with a gap between adjacent electrodes of 98.80 μm. The ZnO-based thin films and NWs were amended by sol–gel and hydrothermal routes. High-quality crystalline and c-axis orientated ZnO thin films were observed by XRD analyses. The ZnO thin film was annealed for 1, 3 and 5 h, yielding a good-quality crystallite with sizes of 50, 100 and 110 nm, and the band gaps were measured as 3.26, 3.20 and 3.17 eV, respectively. Furthermore, a flower-modeled NW was obtained with the lowest diameter of 21 nm. Our designed ZnO NW-modified IDE was shown to have a detection limit as low as 0.03 mg/dL (correlation coefficient = 0.98952) of glucose with a low response time of 3 s, perform better than commercial glucose meter, suitable to instantly monitor the glucose level of diabetes patients. This study demonstrated the high performance of NW-mediated IDEs for glucose sensing as alternative to current glucose sensors
Description
Analytica Chimica Acta
Volume 925, 21 June 2016, Pages 70-81
Keywords
Interdigitated electrode, ZnO nanowire, Glucose, Biosensor, Sol–gel
Citation
R. Haarindraprasad, Uda Hashim, Subash C.B. Gopinath, Veeradasan Perumal, Wei-Wen Liu, S.R. Balakrishnan, Fabrication of interdigitated high-performance zinc oxide nanowire modified electrodes for glucose sensing, Analytica Chimica Acta, Volume 925, 2016, Pages 70-81, ISSN 0003-2670, https://doi.org/10.1016/j.aca.2016.04.030.