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A Stepwise Approach To A National Hepatitis C Screening Strategy In Malaysia To Meet The Who 2030 Targets: Proposed Strategy, Coverage, And Costs

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dc.contributor.authorLindsey Hiebert,en_US
dc.contributor.authorRobert Hecht,en_US
dc.contributor.authorShan Soe-Lin,en_US
dc.contributor.authorRosmawati Mohamed,en_US
dc.contributor.authorFatiha H Shabaruddin,en_US
dc.contributor.authorSyed Mukhtar Syed Mansor,en_US
dc.contributor.authorMaznah Dahlui,en_US
dc.contributor.authorAmirah Azzeri,en_US
dc.contributor.authorScott A McDonalden_US
dc.date.accessioned2024-05-28T08:27:58Z
dc.date.available2024-05-28T08:27:58Z
dc.date.issued2019-05
dc.date.submitted2021-2-9
dc.descriptionValue in Health Regional Issues Volume 18, May 2019, Pages 112-120en_US
dc.description.abstractBackground: In Malaysia, more than 330 000 individuals are estimated to be chronically infected with hepatitis C virus (HCV), but less than 2% have been treated to date. Objectives: To estimate the required coverage and costs of a national screening strategy to inform the launch of an HCV elimination program. Methods: We designed an HCV screening strategy based on a “stepwise” approach. This approach relied on targeting of people who inject drugs in the early years, with delayed onset of widespread general population screening. Annual coverage requirements and associated costs were estimated to ensure that the World Health Organization elimination treatment targets were met. Results: In total, 6 million individuals would have to be screened between 2018 and 2030. Targeting of people who inject drugs in the early years would limit annual screening coverage to less than 1 million individuals from 2018 to 2026. General population screening would have to be launched by 2026. Total costs were estimated at MYR 222 million ($58 million). Proportional to coverage targets, 60% of program costs would fall from 2026 to 2030. Conclusions: This exercise was one of the first attempts to conduct a detailed analysis of the required screening coverage and costs of a national HCV elimination strategy. These findings suggest that the stepwise approach could delay the onset of general population screening by more than 5 years after the program's launch. This delay would allow additional time to mobilize investments required for a successful general population screening program and also minimize program costs. This strategy prototype could inform the design of effective screening strategies in other countriesen_US
dc.identifier.citationHiebert, L., Hecht, R., Soe-Lin, S., Mohamed, R., Shabaruddin, F. H., Mansor, S. M. S., Dahlui, M., Azzeri, A., & McDonald, S. (2019). A stepwise approach to a national Hepatitis C screening strategy in Malaysia to meet the WHO 2030 targets: proposed strategy, coverage, and costs. Value in Health Regional Issues (Print), 18, 112–120. https://doi.org/10.1016/j.vhri.2018.12.005en_US
dc.identifier.doi10.1016/j.vhri.2018.12.005
dc.identifier.epage120
dc.identifier.issn2212-1099
dc.identifier.issue18
dc.identifier.other2446-4
dc.identifier.spage112
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S2212109919300366?via%3Dihub
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/8830
dc.identifier.volume2019
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofValue in Health Regional Issuesen_US
dc.titleA Stepwise Approach To A National Hepatitis C Screening Strategy In Malaysia To Meet The Who 2030 Targets: Proposed Strategy, Coverage, And Costsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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