Publication:
Deciphering The Pan-Genome Of Ganoderma sp. To Depict Potential Genomic Components That Contribute To Ganoderma Boninense Pathogenicity

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dc.contributor.authorSuhaila Sulaimanen_US
dc.contributor.authorNur Syamimi Yusoffen_US
dc.contributor.authorTan Joon Sheongen_US
dc.contributor.authorLee Yang Pingen_US
dc.date.accessioned2024-05-28T05:47:20Z
dc.date.available2024-05-28T05:47:20Z
dc.date.issued2018
dc.descriptionVolume:47 No:5en_US
dc.description.abstractThe soil-borne fungus, Ganoderma boninense is notorious as the cause of basal stem rot (BSR) disease in oil palm that results in severe economic losses. Due to insufficient functional information of its genome, mechanism underlying the infection is still enigmatic. Despite the constraint, here we report the pan-genome of eight draft genomes of Ganoderma sp. that delineated into 35,121 orthologous genes (OGs), consisting 4,898 genes in core genome and 30,223 genes in accessory genome, whilst the latter encompasses of 1,905 species-specific genes. Further genome-wide comparative analysis discovers 607 genes in pathogenic fungi G. boninense but not in its related non-pathogenic Ganoderma sp., suggesting their potential role in G. boninense pathogenicity towards its host. By implementing various bioinformatics tools and public databases, the incorporated functional enrichment of the candidate genes leads to inference of their role during host-pathogen interaction. This enables us to narrow down the entire gene catalogue in Ganoderma sp. for experimental verification in the laboratory. It is undeniable that the harnessing of Ganoderma sp. pan-genome data will conform to a more structured downstream analysis in understanding the role of G. boninense as the key agent of BSR in oil palm.en_US
dc.identifier.epage80
dc.identifier.issn0126-8643
dc.identifier.issue5
dc.identifier.spage71
dc.identifier.urihttps://jms.mabjournal.com/index.php/mab/article/view/2097/506
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/6496
dc.identifier.volume47
dc.language.isoen_USen_US
dc.publisherMalaysian Society of Applied Biologyen_US
dc.relation.ispartofMalaysian Applied Biology Journalen_US
dc.subjectPan-genome, Ganoderma boninense, pathogenicity, basal stem roten_US
dc.titleDeciphering The Pan-Genome Of Ganoderma sp. To Depict Potential Genomic Components That Contribute To Ganoderma Boninense Pathogenicityen_US
dc.typeArticleen_US
dspace.entity.typePublication

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