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The Ethics of Managing Recurrent Respiratory Papillomatosis in Children:A Case Study

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dc.contributor.authorMuhammad Yusoff Mohd Ramdzanen_US
dc.contributor.authorMeenal Mavinkurveen_US
dc.contributor.authorShamini Subramaniamen_US
dc.contributor.authorMohd Anas Che Niken_US
dc.contributor.authorFahisham Taiben_US
dc.contributor.authorHazamaMohamaden_US
dc.contributor.authorSuzina Sheikh Abdul Hamiden_US
dc.date.accessioned2024-05-28T05:59:44Z
dc.date.available2024-05-28T05:59:44Z
dc.date.issued2016
dc.descriptionVolume 8, No. 4en_US
dc.description.abstractRecurrent respiratory papillomatosis (RRP) is a rare cause of childhood stridor which typically presents before the age of five years and results from the vertical transmission of the human papilloma virus. Genotypes 11 and 6 are commonly implicated in RRP. Following vertical transmission, the human papilloma virus (HPV) causes overgrowth of the airway epithelium which causes partial airway obstruction and the symptoms of stridor. The mainstay management is surgical debridement of the papillomata but the recurrence rate subsequent to surgery is high, such that most children will require repeated surgical procedures at regular interval. Medical adjuvant therapy can be used, but data is limited and the medications are used on an off-label basis. This case highlights the ethical considerations that need to be made when using off-label medications in paediatric patients.en_US
dc.identifier.doi10.5959/eimj.v8i4.460
dc.identifier.doihttp://eduimed.usm.my/EIMJ20160804/EIMJ20160804_10.pdf
dc.identifier.epage87
dc.identifier.issn2180-1932
dc.identifier.issue4
dc.identifier.spage83
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/6922
dc.identifier.volume8
dc.language.isoen_USen_US
dc.publisherPenerbit Universiti Sains Malaysiaen_US
dc.relation.ispartofEducation in Medicine Journalen_US
dc.subjectOff label medication, Respiratory papilomatosis, Evidence based medicine, Childrenen_US
dc.titleThe Ethics of Managing Recurrent Respiratory Papillomatosis in Children:A Case Studyen_US
dc.typeArticleen_US
dspace.entity.typePublication

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