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A multi-centre randomised clinical trial of oral hygiene interventions following stroke-A 6-month trial

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dc.Chemicals/CASMouthwashes
dc.FundingDetailsChinese University of Hong Kong
dc.FundingDetailsA randomised clinical control trial was conducted from June 2015 to August 2016 at five public hospitals in Malaysia. Ethical approval was granted from the Medical Research and Ethics Committee (MREC) of the National Institutes of Health, Ministry of Malaysia with a clinical trial registration number of NMRR-13-1664-17247(IIR).
dc.FundingDetailsThe authors have stated explicitly that there are no conflict of interests in connection with this article. The study was funded by The University of Hong Kong.
dc.citedby1
dc.contributor.affiliationsFaculty of Dentistry
dc.contributor.affiliationsThe University of Hong Kong
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsHospital Serdang
dc.contributor.affiliationsUniversity of Malaya (UM)
dc.contributor.affiliationsTung Wah Hospital
dc.contributor.authorProf. Madya Dr. Normaliza Binti Ab Maliken_US
dc.contributor.authorMohamad Yatim S.en_US
dc.contributor.authorAbdul Razak F.en_US
dc.contributor.authorLam O.L.T.en_US
dc.contributor.authorJin L.en_US
dc.contributor.authorLi L.S.W.en_US
dc.contributor.authorMcGrath C.en_US
dc.date.accessioned2024-05-28T08:43:03Z
dc.date.available2024-05-28T08:43:03Z
dc.date.issued2018
dc.description.abstractMaintaining good oral hygiene is important following stroke. This study aimed to evaluate the effectiveness of two oral health promotion (OHP) programmes to reduce dental plaque levels following stroke. A multi-centre randomised clinical control trial was conducted among patients hospitalised following stroke in Malaysia. Patients were randomly allocated to two OHP groups: (i) control group who received the conventional method for plaque control—daily manual tooth brushing with a standardised commercial toothpaste, (ii) test group—who received an intense method for plaque control—daily powered tooth brushing with 1% Chlorhexidine gel. Oral health assessments were performed at baseline, at 3 months and 6 months post-intervention. Within- and between-group changes in dental plaque were assessed over time. Regression analyses were conducted on dental plaque levels at 6 months controlling for OHP group, medical, dental and socio-demographic status. The retention rate was 62.7% (54 of 86 subjects). Significant within-group changes of dental plaque levels were evident among the test group (P <.001) and the control group (P <.001). No significant between-group changes of dental plaque levels were apparent (P >.05). Regression analyses identified that baseline plaque levels (adjusted ß = 0.79, P <.001) and baseline functional dependency level (adjusted ß = −0.34, P <.05) were associated with dental plaques levels at the end of the trial (6 months). Both, “Conventional” and “Intense” oral health promotion programmes may successfully reduce dental plaque during stroke rehabilitation and are of comparable effectiveness. Baseline dental plaque levels and functional dependency level were key factors associated with dental plaque levels at follow-up at 6 months.en_US
dc.description.natureFinalen_US
dc.identifier.CODENJORHB
dc.identifier.doi10.1111/joor.12582
dc.identifier.epage139
dc.identifier.issn0305182X
dc.identifier.issue2
dc.identifier.pmid29090475
dc.identifier.scopus2-s2.0-85034790232
dc.identifier.spage132
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85034790232&doi=10.1111%2fjoor.12582&partnerID=40&md5=8c6569992dd88008da7e3b8f6f5af0dd
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9338
dc.identifier.volume45
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherBlackwell Publishing Ltden_US
dc.relation.ispartofJournal of Oral Rehabilitation
dc.sourceScopus
dc.subjectcerebrovascular diseaseen_US
dc.subjectchlorhexidineen_US
dc.subjectclinical trialen_US
dc.subjectdental plaqueen_US
dc.subjectoral health promotionen_US
dc.subjectrehabilitationen_US
dc.titleA multi-centre randomised clinical trial of oral hygiene interventions following stroke-A 6-month trialen_US
dc.title.alternativeJ. Oral Rehabil.en_US
dc.typeArticleen_US
dspace.entity.typePublication

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