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Polymer-Based Hydrogel Loaded with Honey in Drug Delivery System for Wound Healing Applications

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dc.contributor.authorSiti Nor Najihah Yasinen_US
dc.contributor.authorZulfahmi Saiden_US
dc.contributor.authorNadia Haliben_US
dc.contributor.authorZulaiha A Rahmanen_US
dc.contributor.authorNoor Izzati Mokhzanien_US
dc.date.accessioned2024-05-28T08:34:14Z
dc.date.available2024-05-28T08:34:14Z
dc.date.issued2023
dc.date.submitted2023-11-7
dc.descriptionVolume 15 Issue 14en_US
dc.description.abstractExcellent wound dressings should have crucial components, including high porosity, non-toxicity, high water absorption, and the ability to retain a humid environment in the wound area and facilitate wound healing. Unfortunately, current wound dressings hamper the healing process, with poor antibacterial, anti-inflammatory, and antioxidant activity, frequent dressing changes, low biodegradability, and poor mechanical properties. Hydrogels are crosslinked polymer chains with three-dimensional (3D) networks that have been applicable as wound dressings. They could retain a humid environment on the wound site, provide a protective barrier against pathogenic infections, and provide pain relief. Hydrogel can be obtained from natural, synthetic, or hybrid polymers. Honey is a natural substance that has demonstrated several therapeutic efficacies, including anti-inflammatory, antibacterial, and antioxidant activity, which makes it beneficial for wound treatment. Honey-based hydrogel wound dressings demonstrated excellent characteristics, including good biodegradability and biocompatibility, stimulated cell proliferation and reepithelization, inhibited bacterial growth, and accelerated wound healing. This review aimed to demonstrate the potential of honey-based hydrogel in wound healing applications and complement the studies accessible regarding implementing honey-based hydrogel dressing for wound healing.en_US
dc.identifier.citationNor, S., Said, Z., Halib, N., Zulaiha Abdul Rahman, & Noor Izzati Mokhzani. (2023). Polymer-Based Hydrogel Loaded with Honey in Drug Delivery System for Wound Healing Applications. Polymers, 15(14), 3085–3085. https://doi.org/10.3390/polym15143085en_US
dc.identifier.doi10.3390/polym15143085
dc.identifier.epage23
dc.identifier.issn2073-4360
dc.identifier.issue14
dc.identifier.spage1
dc.identifier.urihttps://www.mdpi.com/2073-4360/15/14/3085
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85166227219&origin=resultslist&sort=plf-f&src=s&sid=33a9dd92a4e61ea08e07f7b7d03d8752&sot=b&sdt=b&s=TITLE-ABS-KEY%28Polymer-based+Hydrogel+Loaded+With+Honey+In+Drug+Delivery+System+For+Wound+Healing+Applications%29&sl=110&sessionSearchId=33a9dd92a4e61ea08e07f7b7d03d8752
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9084
dc.identifier.volume15
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.relation.ispartofPolymersen_US
dc.subjectwound healing; wound dressings; hydrogel; honey; natural polymer; synthetic polymeren_US
dc.titlePolymer-Based Hydrogel Loaded with Honey in Drug Delivery System for Wound Healing Applicationsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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