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Electrospun Nanofiber Composites for Drug Delivery A Review on Current Progresses

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dc.contributor.authorRenatha Jiffrinen_US
dc.contributor.authorSaiful Izwan Abd Razaken_US
dc.contributor.authorMohamad Ikhwan Jamaludinen_US
dc.contributor.authorAmir Syahir Amir Hamzahen_US
dc.contributor.authorMuadz Ahmad Mazianen_US
dc.contributor.authorMuhammad Azan Tamar Jayaen_US
dc.contributor.authorMohammed Z. Nasrullahen_US
dc.contributor.authorMohammed Majrashien_US
dc.contributor.authorAbdulrahman Theyaben_US
dc.contributor.authorAhmed A. Aldarmahien_US
dc.contributor.authorZuhier Awanen_US
dc.contributor.authorMohamed M. Abdel-Daimen_US
dc.contributor.authorAbul Kalam Azaden_US
dc.date.accessioned2024-05-28T04:29:21Z
dc.date.available2024-05-28T04:29:21Z
dc.date.issued2022
dc.date.submitted2022-10-25
dc.descriptionJournals Polymers Volume 14 Issue 18en_US
dc.description.abstractA medication’s approximate release profile should be sustained in order to generate the desired therapeutic effect. The drug’s release site, duration, and rate must all be adjusted to the drug’s therapeutic aim. However, when designing drug delivery systems, this may be a considerable hurdle. Electrospinning is a promising method of creating a nanofibrous membrane since it enables drugs to be placed in the nanofiber composite and released over time. Nanofiber composites designed through electrospinning for drug release purposes are commonly constructed of simple structures. This nanofiber composite produces matrices with nanoscale fiber structure, large surface area to volume ratio, and a high porosity with small pore size. The nanofiber composite’s large surface area to volume ratio can aid with cell binding and multiplication, drug loading, and mass transfer processes. The nanofiber composite acts as a container for drugs that can be customized to a wide range of drug release kinetics. Drugs may be electrospun after being dissolved or dispersed in the polymer solution, or they can be physically or chemically bound to the nanofiber surface. The composition and internal structure of the nanofibers are crucial for medicine release patterns.en_US
dc.identifier.citationJiffrin, R.; Razak, S.I.A.; Jamaludin, M.I.; Hamzah, A.S.A.; Mazian, M.A.; Jaya, M.A.T.; Nasrullah, M.Z.; Majrashi, M.; Theyab, A.; Aldarmahi, A.A.; Awan, Z.; Abdel-Daim, M.M.; Azad, A.K. Electrospun Nanofiber Composites for Drug Delivery: A Review on Current Progresses. Polymers 2022, 14, 3725. https://doi.org/10.3390/polym14183725en_US
dc.identifier.doi10.3390/polym14183725
dc.identifier.epage29
dc.identifier.issn2073-4360
dc.identifier.issue14
dc.identifier.other2325-11
dc.identifier.spage1
dc.identifier.urihttps://www.mdpi.com/2073-4360/14/18/3725
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/5743
dc.identifier.volume3725
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofPolymersen_US
dc.subjectelectrospinning; nanofiber; drug delivery; drug release; nanofiber compositeen_US
dc.titleElectrospun Nanofiber Composites for Drug Delivery A Review on Current Progressesen_US
dc.typeArticleen_US
dspace.entity.typePublication

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