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Factors associated with good response in methadone therapy in a Malaysian district hospital

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dc.FundingDetailsThe authors would like to express their gratitude to the Malaysian Ministry of Health and Hospital Sultan Haji Ahmad Shah for supporting this research. Special thanks as well to Dr Lazli Bakar, Professor Jamaludin Abdul Rahman for their supervision and guidance. Highest appreciation to Asiah Tahir and others who had assisted in this study. This is a self-funded study and is registered under the National Medical Research Register (NMMR-10-1370-7207).
dc.contributor.affiliationsFaculty of Medicine and Health Sciences
dc.contributor.affiliationsHospital Sultan Haji Ahmad Shah
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.authorGhani F.A.en_US
dc.contributor.authorIsmail L.en_US
dc.contributor.authorAziz N.en_US
dc.contributor.authorTajjudin I.en_US
dc.contributor.authorRashid M.A.R.en_US
dc.date.accessioned2024-05-29T02:00:53Z
dc.date.available2024-05-29T02:00:53Z
dc.date.issued2019
dc.descriptionMal J Med Health Sci 15(3): 14-19, Oct 2019en_US
dc.description.abstractIntroduction: Methadone maintenance treatment is effective in reducing opiate use, related crime and HIV risk behaviors. However, the number of patients dropping out of treatment or continue misusing drugs are significant. Primary screening of such patients could be useful in the development of guidelines targeted to prevent such incident. The aim of this study was to determine the prevalence of good treatment responders and whether socio-demographic factors and methadone dosage are associated with good responses. Methods: Respondents were studied from November 2009 until April 2010 and involved all patients that had undergone methadone therapy from November 2005 to November 2009. Data was obtained from medical and pharmacy records. Missing data was obtained directly from patients via direct interviewing. Patients were considered to have a good response if they stay in the programme and have negative urinalysis result within 6 months of enrolment. Results: 66 out of 104 patients have a good response in methadone therapy. There is an association between good response in methadone therapy and educational level (p=0.045) and district of origin (p=0.041). However, there were no associations with methadone dosage. Conclusion: Higher educational level of at least secondary school education was found to be a good predictor of good response to methadone therapy. Patients who originated from nearby areas have better outcomes. This could be due to the direct observation therapy which could have an effect on non-compliance of patients who lived far away. This suggests the need to provide methadone therapy in local areas for better accessibility and compliance. 2019 UPM Press. All rights reserved.en_US
dc.description.natureFinalen_US
dc.identifier.epage19
dc.identifier.issn16758544
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85073679376
dc.identifier.spage14
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85073679376&partnerID=40&md5=bed298a7a9f41c8583924a35b6380bee
dc.identifier.urichrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/viewer.html?pdfurl=https%3A%2F%2Fmedic.upm.edu.my%2Fupload%2Fdokumen%2F2019100108323403_MJMHS_0050.pdf&clen=268903&chunk=true
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/10142
dc.identifier.volume15
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherUPM Pressen_US
dc.relation.ispartofMalaysian Journal of Medicine and Health Sciencesen_US
dc.sourceScopus
dc.subjectMethadoneen_US
dc.subjectMethadone doseen_US
dc.subjectPredictor of complianceen_US
dc.subjectSociodemographic factorsen_US
dc.titleFactors associated with good response in methadone therapy in a Malaysian district hospitalen_US
dc.typeArticleen_US
dspace.entity.typePublication

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