Publication:
Spleen Autotransplantation In Rat

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cris.virtual.departmentUniversiti Sains Islam Malaysia
cris.virtual.orcid0000-0003-1016-9873
cris.virtualsource.department23b09d4f-91d0-4abb-8508-6108bc3bec6b
cris.virtualsource.orcid23b09d4f-91d0-4abb-8508-6108bc3bec6b
dc.contributor.authorAdlina Mohammaden_US
dc.contributor.authorAffirul Chairil Ariffinen_US
dc.contributor.authorFadlul Azim Fauzi Mansuren_US
dc.contributor.authorWan Omar Abdullahen_US
dc.contributor.authorAsral Wirda Ahmad Asnawien_US
dc.contributor.authorAnuar Sanien_US
dc.contributor.authorRazrim Rahim
dc.date.accessioned2024-05-28T03:32:26Z
dc.date.available2024-05-28T03:32:26Z
dc.date.issued2020
dc.date.submitted18/2/2021
dc.descriptionVolume : 2 No: 2 (page: 1-5)en_US
dc.description.abstractAim: This paper describes the surgical procedure for spleen auto transplantation in rats. Splenectomy is an important surgery protocol in research studies involving immunology and hematopoietic diseases. Spleen auto transplantation is an alternative method undertaken to preserve the splenic function as the absence of spleen (asplenia) is associated with lifelong risk for sepsis, especially by encapsulated bacteria. Method: Four six weeks old male Sprague-Dawley rats, with range of weight from 248-281 grams, underwent spleen autotransplantation via midline laparotomy incision. In this procedure the spleen was completely removed (total splenectomy); it involved removing the spleen and re-transplanted in greater omentum. A piece of the spleen weighing approximately 0.34 grams was transplanted inside the greater omentum and held in place with an absorbable suture knot. The muscle layer and skin incision were then closed using absorbable suture. The surgery was conducted under deep sedation and the rat was monitored post-operatively until it fully recovered. Outcome: The post-operative recovery of the rat was uneventful. Six-weeks after the surgery, the rat underwent a re-look laparotomy and the auto-transplanted spleen was examined. There was a three-fold increase in the size and weight of the spleen. Conclusion: This spleen auto transplantation model, which utilized an omental pouch, was not only successful in preserving the spleen, but also allowed for spleen regeneration. This model provides future platform for further research in auto-transplanted spleen.en_US
dc.identifier.citationMohammad, A., Ariffin, A. C., Mansur, F. A. F., Abdullah, W. O., Ahmad Asnawi, A. W., Sani, A., & Rahim, R. (2021). Spleen Autotransplantation in Rat. Journal of Surgery and Trauma Care, 2(2). Retrieved from https://fazpublishing.com/jstc/index.php/jstc/article/view/37en_US
dc.identifier.epage5
dc.identifier.issn2672-7366
dc.identifier.issue2
dc.identifier.other2267-11
dc.identifier.spage1
dc.identifier.urihttps://fazpublishing.com/jstc/index.php/jstc/article/view/37/18
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/4628
dc.identifier.volume2
dc.language.isoen_USen_US
dc.publisherFaz Publishingen_US
dc.relation.ispartofJournal of Surgery and Trauma Careen_US
dc.subjectspleen autotranplantation, splenectomy, rodent, immune system, surgeryen_US
dc.titleSpleen Autotransplantation In Raten_US
dc.typeArticleen_US
dspace.entity.typePublication
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oairecerif.author.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#
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oairecerif.author.affiliation#PLACEHOLDER_PARENT_METADATA_VALUE#
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oairecerif.author.affiliationUniversiti Sains Islam Malaysia

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