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Candida Skull Base Osteomyelitis: A Case Report And Literature Review

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dc.contributor.authorMadhusudhan Krishnamoorthy,en_US
dc.contributor.authorNik Adilah Nik Othman ,en_US
dc.contributor.authorNor Eyzawiah binti Hassan,en_US
dc.contributor.authorShahrul bin Hitamen_US
dc.date.accessioned2024-05-27T14:36:22Z
dc.date.available2024-05-27T14:36:22Z
dc.date.issued2020-08
dc.date.submitted2021-2-9
dc.descriptionActa Med. 2020, 63: 82-85en_US
dc.description.abstractSkull base osteomyelitis (SBO) also commonly known as malignant otitis externa was first described by Meltzer and Kelemen in 1959. Prior to the advent of the antibiotic era, this disease carried a poor prognosis with significant morbidity. It often proved fatal with mortality rates as high as 50%. Commonly seen in the immunocompromised patients, diabetes mellitus is an important associated comorbidity in the pathophysiologic development of this disease. Treatment is instituted by medical therapy with surgery having a limited role. Surgical intervention has a limited role, for example, in fungal SBO. Such cases may require local debridement and intraoperative tissue biopsies for histopathologic confirmation. This is to demonstrate fungal invasion into the skull base, as well as to exclude other sinister differential diagnoses like squamous cell carcinoma of temporal bone. In this case report, we present a rare case of candida SBO and the literature review.en_US
dc.identifier.doihttps://doi.org/10.14712/18059694.2020.22
dc.identifier.epage85
dc.identifier.issn1211-4286
dc.identifier.issue2
dc.identifier.other1390-13
dc.identifier.spage82
dc.identifier.urihttps://actamedica.lfhk.cuni.cz/63/2/0082/
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/3413
dc.identifier.volume63
dc.language.isoenen_US
dc.publisherUniversiti Sains Islam Malaysiaen_US
dc.relation.ispartofACTA MEDICAen_US
dc.subjectskull base;en_US
dc.subjectosteomyelitis;en_US
dc.subjectfungal;en_US
dc.subjectcandida;en_US
dc.subjectotitis externaen_US
dc.titleCandida Skull Base Osteomyelitis: A Case Report And Literature Reviewen_US
dc.typeArticleen_US
dspace.entity.typePublication

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