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Study on anti-quorum sensing potentials and phytochemical constituents of Euphorbia hirta

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dc.contributor.authorNur Aishah Abdul Wahaben_US
dc.contributor.authorHanina Mohd Nooren_US
dc.contributor.authorSalina Mat Radzien_US
dc.contributor.authorJalil Kaderen_US
dc.date.accessioned2024-05-27T14:39:22Z
dc.date.available2024-05-27T14:39:22Z
dc.date.issued2014
dc.descriptionVolume: 4, No :3en_US
dc.description.abstractEuphorbia hirta is an annual broad-leaved herb and widely used as traditional medicine to treat various ailments. This herb was tested on the anti quorum sensing (anti-QS) potentials in fresh (edible or macerated) forms and acetone extracts via biomonitor strain Chromabacterium violaceum (ATCC 12472). The biomonitor strain has an ability to produce purple pigment (violacein) under QS-control. The different parts of E. hirta extracts were then subjected to preliminary phytochemical screening using standard procedures and finally analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). Preliminary screening on fresh parts of this herb revealed that leaves exhibited the highest anti-QS activities towards C. violaceum. The results also exhibited the wide variation in the anti-QS activities on whole plants, flowers, stems, leaves and roots of E. hirta from acetone extraction. The highest anti-QS activities were recorded by leaves and flowers extracts as the lowest of minimum QS inhibition concentration values (1.8906 mg/ml) were indicated by both extracts respectively. Phytochemical screening of E. hirta extracts revealed the presence of carbohydrates, lipids, protein, flavonoids, alkaloids, saponins, resins, steroids, acidic compounds, tannins, glycosides, phenols and terpenoids. The quantitave phytochemical assays via GC-MS indicated that this herb rich with fatty acids, terpenoids and phenolic compounds.en_US
dc.identifier.doihttps://www.iiste.org/Journals/index.php/JNSR/article/view/11067
dc.identifier.epage83
dc.identifier.issn2224-3186
dc.identifier.issue3
dc.identifier.spage76
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/3539
dc.identifier.volume4
dc.language.isoen_USen_US
dc.publisherInternational Institute for Science, Technology and Educationen_US
dc.relation.ispartofJournal of Natural Sciences Researchen_US
dc.subjectEuphorbia hirta, Chromabacterium violaceum, anti-quorum sensing, phytochemical assaysen_US
dc.titleStudy on anti-quorum sensing potentials and phytochemical constituents of Euphorbia hirtaen_US
dc.typeArticleen_US
dspace.entity.typePublication

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