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Periodontitis And Its Inflammatory Changes Linked To Various Systemic Diseases: A Review Of Its Underlying Mechanisms

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dc.contributor.authorRuchi Bhuyanen_US
dc.contributor.authorSanat Kumar Bhuyanen_US
dc.contributor.authorJatindra Nath Mohantyen_US
dc.contributor.authorSrijit Dasen_US
dc.contributor.authorNorsham Julianaen_US
dc.contributor.authorIzuddin Fahmy Abuen_US
dc.date.accessioned2024-05-28T06:36:46Z
dc.date.available2024-05-28T06:36:46Z
dc.date.issued2022
dc.date.submitted2023-1-31
dc.descriptionVolume: 10en_US
dc.description.abstractPeriodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is increasing all over the world. In patients with periodontitis, there is gradual destruction of the periodontal ligament and the alveolar bone, and later, in advanced stages, there is tooth loss. Different microorganisms, the host’s immune response, and various environmental factors interact in the progression of this chronic inflammatory disease. In the present review, we discuss the epidemiology, clinical features, diagnosis, and complications of periodontitis. We also discuss the association of chronic inflammation found in periodontitis with various other systemic diseases, which include cardiovascular, respiratory, diabetes, Alzheimer’s, cancer, adverse pregnancy, and multiple myeloma, and also highlight microbial carcinogenesis and the microRNAs involved. The latest updates on the molecular mechanism, possible biomarkers, and treatment procedures may be beneficial for diagnostic and therapeutic purposes.en_US
dc.identifier.citationBhuyan, R.; Bhuyan, S.K.; Mohanty, J.N.; Das, S.; Juliana, N.; Abu, I.F. Periodontitis and Its Inflammatory Changes Linked to Various Systemic Diseases: A Review of Its Underlying Mechanisms. Biomedicines 2022, 10, 2659. https://doi.org/10.3390/ biomedicines10102659en_US
dc.identifier.doi10.3390/biomedicines10102659
dc.identifier.doihttps://www.mdpi.com/2227-9059/10/10/2659
dc.identifier.epage18
dc.identifier.issn2227-9059
dc.identifier.issue10
dc.identifier.spage1
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/7319
dc.identifier.volume10
dc.language.isoen_USen_US
dc.publisherMDPIen_US
dc.relation.ispartofBiomedicinesen_US
dc.subjectperiodontitis; oral; infection; mechanisms; pathology; managementen_US
dc.titlePeriodontitis And Its Inflammatory Changes Linked To Various Systemic Diseases: A Review Of Its Underlying Mechanismsen_US
dc.typeBooken_US
dspace.entity.typePublication

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