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Oral Health Interventions Using Chlorhexidine-Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trial

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dc.contributor.affiliationsFaculty of Dentistry
dc.contributor.affiliationsThe University of Hong Kong
dc.contributor.affiliationsUniversiti Sains Islam Malaysia (USIM)
dc.contributor.affiliationsUniversity of Malaya (UM)
dc.contributor.affiliationsHospital Serdang
dc.contributor.affiliationsTung Wah Hospital
dc.contributor.authorProf. Madya Dr. Normaliza Binti Ab Maliken_US
dc.contributor.authorAbdul Razak F.en_US
dc.contributor.authorMohamad Yatim S.en_US
dc.contributor.authorLam O.L.T.en_US
dc.contributor.authorJin L.en_US
dc.contributor.authorLi L.S.W.en_US
dc.contributor.authorMcGrath C.en_US
dc.date.accessioned2024-05-28T08:35:20Z
dc.date.available2024-05-28T08:35:20Z
dc.date.issued2018
dc.description.abstractObjective: To evaluate the presence of oral opportunistic pathogens among stroke survivors, both before and after oral health care interventions. Methods: A multicenter randomized clinical trial was conducted on hospitalized stroke survivors. Those in the control group were given standard care of oral hygiene (a manual toothbrush and toothpaste), whereas those in the test group were given intense care of oral hygiene (a powered toothbrush and 1% chlorhexidine oral gel). Oral clinical assessments were carried out, and microbiological samples were collected, using concentrated oral rinse samples at 3 time points: baseline, 3 months, and 6 months. Results: The prevalence of oral yeast was significantly reduced in the test group at 6 months (P <.05), but no significant difference was observed over time. A significant reduction was observed in the prevalence of Staphylococcus aureus (P <.01) and aerobic and facultative gram-negative bacilli over time (P <.05), but there were no significant differences noted between groups at 6 months. Candida albicans and Klebsiella pneumoniae were the prominent pathogens determined throughout the trial. Kluyvera strains have also been isolated from this cohort. Conclusion: Oral hygiene intervention using a powered tooth brush and 1% chlorhexidine oral gel was effective in reducing the prevalence of oral opportunistic pathogens. � 2017 Elsevier Inc.
dc.description.natureFinalen_US
dc.identifier.doi10.1016/j.jebdp.2017.08.002
dc.identifier.epage109
dc.identifier.issn15323382
dc.identifier.issue2
dc.identifier.pmid29747810
dc.identifier.scopus2-s2.0-85029223872
dc.identifier.spage99
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85029223872&doi=10.1016%2fj.jebdp.2017.08.002&partnerID=40&md5=b44ed23517150a74fe99d85d70861607
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/9122
dc.identifier.volume18
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherMosby Inc.en_US
dc.relation.ispartofJournal of Evidence-Based Dental Practice
dc.sourceScopus
dc.subjectOral healthen_US
dc.subjectOral hygieneen_US
dc.subjectOral pathogensen_US
dc.subjectRehabilitationen_US
dc.subjectStrokeen_US
dc.titleOral Health Interventions Using Chlorhexidine-Effects on the Prevalence of Oral Opportunistic Pathogens in Stroke Survivors: A Randomized Clinical Trialen_US
dc.title.alternativeJ. Evid.-Based Dent. Pract.en_US
dc.typeArticleen_US
dspace.entity.typePublication

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