Publication:
Evaluation Of Antitumor Activity Of Copper Complexes Of Coumarin In Breast And Lung Cancer

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Evaluation Of Antitumor Activity Of Copper Complexes Of Coumarin In Breast And Lung Cancer.pdf (423.94 KB)

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2015

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IDOSI Publications

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Abstract

Considerable interest has been aroused for copper complexes of coumarins due to their wide variety of biological activity. Three copper complexes of coumarin; A1, A2 and A3 were synthesized and evaluated for antitumor activity by using MTT assay. These complexes show antitumor activity against breast cancer MCF7 with IC values of 1.87, 1.87 and 30?g/ml respectively and exhibit 50 antitumor activity against lung cancer A549 with IC50 values of 7.5, 15 and 1.87?g/ml respectively.

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Coumarin;, Copper complexes;, Antitumor

Citation

Middle-East Journal of Scientific Research 23 (12): 2946-2951, 2015 ISSN 1990-9233 © IDOSI Publications, 2015 DOI: 10.5829/idosi.mejsr.2015.23.12.22879

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https://www.idosi.org/mejsr/mejsr23(12)15/20.pdf
 https://oarep.usim.edu.my/handle/123456789/4753

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