Publication:
In-Vitro Antibacterial Activities Of Ajwa Date Fruit (Phoenix Dactylifera L.) Extract Against Selected Gram-Negative Bacteria Causing Gastroenteritis

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dc.contributor.authorAbdullah, Nen_US
dc.contributor.authorIshak, NFMen_US
dc.contributor.authorShahida, WSWen_US
dc.date.accessioned2024-05-29T02:53:09Z
dc.date.available2024-05-29T02:53:09Z
dc.date.issued2019
dc.description.abstractGastroenteritis, especially those caused by bacterial pathogens, remains as one of the major health issues in developing countries. Despite the availability of treatment, people are turning their interest in consuming certain food for its therapeutic value given the adverse effects of medications. This includes the consumption of date fruits (Phoenix dactylifera L.). This study aims to determine the antibacterial effect of two methods of extraction, i.e., hot aqueous extract and methanol extract of Ajwa date fruit against selected gramnegative bacteria causing gastroenteritis. The antimicrobial activities were determined quantitatively using well diffusion assay together with the minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC). Results showed that both hot aqueous and methanol extracts have the potential to suppress the growth of all tested bacteria. The methanol extract had higher inhibitory zones compared to hot aqueous extract, and the zones of inhibition were noted to increase with increase in the extract concentration. S. flexneri was the most sensitive bacteria to both types of extract. The methanol extract was also more effective in suppressing the bacterial growth and has a higher potential in killing the bacteria compared to hot aqueous extract. These results suggest that Ajwa date extract has a bacteriostatic property at lower concentration and bactericidal property at higher concentration. In conclusion, Ajwa date fruit extract has the antibacterial potential against selected bacterial causing gastroenteritis. Further study on the phytochemical properties that contribute to this effect is currently in progress.
dc.identifier.doi10.13040/IJPSR.0975-8232.10(6).2951-55
dc.identifier.epage2955
dc.identifier.issn0975-8232
dc.identifier.issue6
dc.identifier.scopusWOS:000470005300041
dc.identifier.spage2951
dc.identifier.urihttps://oarep.usim.edu.my/handle/123456789/11370
dc.identifier.volume10
dc.languageEnglish
dc.language.isoen_USen_US
dc.publisherInt Journal Pharmaceutical Sciences & Researchen_US
dc.relation.ispartofInternational Journal Of Pharmaceutical Sciences And Research
dc.sourceWeb Of Science (ISI)
dc.subjectPhoenix dactylifera L.en_US
dc.subjectAjwa date fruiten_US
dc.subjectGastroenteritisen_US
dc.subjectAntibacterialen_US
dc.titleIn-Vitro Antibacterial Activities Of Ajwa Date Fruit (Phoenix Dactylifera L.) Extract Against Selected Gram-Negative Bacteria Causing Gastroenteritisen_US
dc.title.alternativeInt. J. Pharm.l Sci. Res.en_US
dc.typeArticleen_US
dspace.entity.typePublication

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